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Could a simple blood injection reverse early menopause?

NCT ID NCT04031456

Recruiting now Disease control Sponsor: Genesis Athens Clinic Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This trial investigates whether injecting a woman's own platelet-rich plasma (PRP) into her ovaries can restart menstrual cycles and improve hormone levels. It includes 100 women under 40 with premature ovarian failure (early menopause). Participants receive either PRP or a placebo injection, and researchers monitor for return of regular periods and changes in key hormones over three months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Platelet-rich plasma (PRP)
What this could lead to
If it works, this could offer a way to restart ovarian function and menstrual cycles in women with premature ovarian failure, potentially restoring fertility without long-term hormone therapy.
What could go wrong
This is an early-to-mid-stage trial with only 100 participants, so results may not apply to everyone. The procedure is invasive, and there is a risk that PRP may not work or could cause ovarian damage or infection.

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Conditions

The condition(s) this trial relates to.

premature menopause premature ovarian failure 1 primary ovarian failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MENOPAUSAL SYNDROME MENOPAUSE RELATED CONDITIONS MENOPAUSE, PREMATURE OVARIAN FAILURE, PREMATURE PREMATURE OVARIAN FAILURE

Contacts and locations

Study contacts

  • Contact

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Genesis AC

    RECRUITING

    Athens, 15232, Greece

    Contact

    Contact

    Contact

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