Could a simple hormone boost improve IVF success?
NCT ID NCT04806919
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether giving a higher dose of vaginal progesterone (800 mg vs 1200 mg daily) can improve pregnancy rates in women with low progesterone levels on the day of embryo transfer. It involved 87 women undergoing a single frozen embryo transfer. The goal was to see if the higher dose leads to more ongoing pregnancies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
micronized progesterone (Amelgen)
What this could lead to
If successful, this could show that a higher progesterone dose helps more women achieve ongoing pregnancy after embryo transfer.
What could go wrong
This is a small, completed Phase 3 trial with only 87 participants, so results may not apply to all IVF patients. Increasing dose may not improve outcomes and could cause side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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AZ Delta
Roeselare, Belgium
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UZ Ghent
Ghent, 9000, Belgium