Otitis media

This study tests whether online training and regular feedback reports can help doctors prescribe fewer antibiotics for common infections like ear infections, strep throat, sinusitis, and pneumonia in children. About 420 children aged 6 months to 12 years are included. The goal is…

This study tests a new device called Solo+ that places tiny tubes in the eardrums of children with ear infections. The goal is to see if it is safe and effective when done in a doctor's office instead of an operating room. About 66 children aged 6 months to 12 years will be enrol…

This study tests whether giving a probiotic (Saccharomyces boulardii) along with a common antibiotic can protect the gut bacteria of children aged 4 to 12 being treated for ear or sinus infections. The goal is to see if it reduces antibiotic-associated diarrhea and limits the spr…

This study tests whether a pharmacist-led program can help people reduce their risk of heart disease. Over 1,000 adults with conditions like diabetes, high blood pressure, or obesity are taking part. Pharmacists use a step-by-step guide to assess risk and support lifestyle change…

This study compares a digital otoscope (a high-tech ear scope) to a standard one for diagnosing ear infections in young children. Four pediatric clinics in Massachusetts will take part, with two using the digital device and two using the usual scope. The goal is to see if the dig…

This study tests a device called OtoSight that helps doctors see inside a child's ear more clearly. The goal is to see if using it leads to fewer unnecessary antibiotic prescriptions, better outcomes, and lower costs. About 700 children aged 6 months to 17 years with ear pain are…

This study tests an advanced ultrasound otoscope, a device that uses sound waves to look inside the ear and detect fluid behind the eardrum. Researchers will compare its readings to the surgeon's findings during ear tube surgery in 300 children up to 12 years old. The goal is to …

This study tests whether adding a superficial cervical plexus block to standard care reduces opioid use and pain in children aged 3 months to 18 years undergoing ear surgery (cochlear implant or tympanomastoidectomy). Half the children get the block plus standard care, the other …

This study looks at where ear tubes are placed in children with ear infections. Normally, tubes go in the front part of the eardrum, but this trial places them in the back part in one ear to see if it lowers the risk of a hole that won't heal. About 386 children will be followed …

This study follows up to 500 people with acute or chronic inflammatory disorders, such as infections or immune problems, over time. Researchers will monitor participants with standard tests and may screen them for other studies. The goal is to better understand these conditions a…

This study collects blood, urine, and tissue samples from 330 adults with advanced lung or head and neck cancer to improve precision medicine. Researchers will analyze genetic changes in these samples and grow some tumors in mice to compare DNA. The goal is to refine liquid biops…

This project works to make sure children with common respiratory infections get the right antibiotics for the right amount of time. It involves over 259,000 kids across many clinics. The goal is to learn the best ways to help doctors follow antibiotic guidelines and reduce unnece…

This study aimed to translate and validate a French version of the COMQ-12 questionnaire, which measures quality of life in children with chronic otitis media (ongoing ear infections). Researchers planned to have children aged 7 to 15 with and without ear infections fill out the …