Osteomyelitis

This study tested a program to help people with opioid use disorder stay on their medication after being hospitalized for serious infections like endocarditis or bone infections. Forty adults took part to see if the program was practical and helpful. The goal is to improve long-t…

This study tested a new clinic that sees emergency room patients the next day for conditions like pneumonia, heart failure, and kidney injury. The goal was to avoid hospital stays and improve patient care. About 570 adults took part, and researchers measured how many days they we…

This study tested whether adding the antibiotic rifampin to standard treatment helps prevent amputations in diabetic patients with foot bone infections. Over 800 veterans participated, receiving either rifampin or a placebo for six weeks. The goal was to see if rifampin improves …

This study tested the antibiotic omadacycline in 42 hospitalized adults with diabetic foot infections, some with bone infection. The goal was to see if it causes fewer kidney problems and gut infections compared to standard antibiotics. Researchers compared results to a group of …

This study looked at using a surgical approach from the back (posterior) to treat bacterial infections of the spine. 47 patients underwent the procedure, which involved removing infected tissue and stabilizing the spine. The researchers found no major complications and reported s…

This study looked at whether a structured physical therapy program before surgery could help an 11-year-old girl with a deformed upper arm bone. The girl had chronic bone infection that left her with shoulder deformity. Over 12 sessions, she received treatments like electrical ne…

This study follows up to 5,000 people with autoinflammatory diseases (like NOMID, CANDLE, and juvenile dermatomyositis) and their healthy relatives. Researchers will collect medical history, blood samples, and imaging over 2-5 day visits to learn how these diseases work and find …

This completed study followed 73 adults with bone or joint infections who needed antibiotics for at least 6 weeks. Researchers tracked how often side effects occurred, how severe they were, and whether they affected quality of life. The goal was to understand why some patients st…

This study looked at whether people who inject opioids can safely finish a course of IV antibiotics at home instead of staying in the hospital. Ten participants received home antibiotic therapy along with addiction medication and support from a health coach and case manager. The …

This study examined tissue samples from 50 patients with staphylococcal bone and joint infections to see if bacteria can hide inside human cells. Researchers used special staining to detect intracellular staphylococci and identify which cell types they occupy. The goal was to bet…

This study collected stool samples from 14 patients with bone or joint infections who were receiving long-term antibiotics injected under the skin. The goal was to build a biological sample bank for future research on how gut bacteria develop resistance to antibiotics. No treatme…