Home IV antibiotics for opioid users: a tiny pilot shows promise

NCT ID NCT05300581

First seen Jan 11, 2026 · Last updated Jun 24, 2026 · Updated 25 times

Summary

This study looked at whether people who inject opioids can safely finish a course of IV antibiotics at home instead of staying in the hospital. Ten participants received home antibiotic therapy along with addiction medication and support from a health coach and case manager. The goal was to see if this approach is feasible and acceptable, not to prove it works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Washington Univeristy

    St Louis, Missouri, 63110, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Outpatient parenteral antibiotic therapy (OPAT) with medications for opioid use disorder and social support

What this could lead to

If successful, this could show that providing addiction treatment and social support makes home IV antibiotics safe and feasible for people who inject drugs, reducing hospital stays.

What could go wrong

This is a very small pilot study with only 10 participants, so results may not apply to larger groups. It only measures feasibility, not effectiveness, and relies on self-reported compliance.

Conditions

The condition(s) this trial relates to.

endocarditis epidural abscess infectious discitis infective arthritis opiate dependence osteomyelitis staphylococcus aureus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.