Home IV antibiotics for opioid users: a tiny pilot shows promise

NCT ID NCT05300581

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether people who inject opioids can safely finish a course of IV antibiotics at home instead of staying in the hospital. Ten participants received home antibiotic therapy along with addiction medication and support from a health coach and case manager. The goal was to see if this approach is feasible and acceptable, not to prove it works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Outpatient parenteral antibiotic therapy (OPAT) with medications for opioid use disorder and social support
What this could lead to
If successful, this could show that providing addiction treatment and social support makes home IV antibiotics safe and feasible for people who inject drugs, reducing hospital stays.
What could go wrong
This is a very small pilot study with only 10 participants, so results may not apply to larger groups. It only measures feasibility, not effectiveness, and relies on self-reported compliance.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Washington Univeristy

    St Louis, Missouri, 63110, United States

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