Ocular motility disease

This study compared two surgical methods to correct exotropia, a condition where one eye turns outward. In one group, a piece of the inner eye muscle was removed and reattached; in the other, the muscle was folded and shortened. Both groups also had the outer eye muscle loosened.…

This study looked at whether a high-fat diet changes how children with mitochondrial disease burn energy. 36 children aged 5 to 21 were randomly assigned to eat either a normal or high-fat diet for a month, then switched. Researchers measured their resting energy use and body com…

This study looked at whether eye exercises after strabismus (crossed eyes) surgery help maintain eye alignment and control over time. Forty children aged 5 to 15 who had surgery and completed a 3-month exercise program were followed. Researchers measured eye deviation and control…

This study tested a new surgical technique called lateral rectus muscle strangulation to treat exotropia, a condition where one or both eyes turn outward. Twelve people aged 4 and older with intermittent exotropia or exophoria underwent the procedure. The goal was to weaken the e…

This study looked at whether wearing an eye patch full-time can improve control of intermittent exotropia (a type of eye misalignment) in children aged 3 to 9. Over 3 months, researchers compared patching to simply watching and waiting. The goal was to see if patching leads to be…

This Phase 3 trial tested a daily injection called elamipretide in 102 adults with primary mitochondrial myopathy, a genetic condition that causes muscle weakness and fatigue. Participants received either the drug or a placebo for 48 weeks. The main goal was to see if the drug co…

This study tested a virtual reality training program called Nu.T in 54 children aged 6 to 15 with intermittent exotropia, a condition where one eye occasionally turns outward. Half of the children used the Nu.T software to do visual exercises, while the other half received no tre…

This study looked at two surgical methods to correct a type of eye misalignment called V-pattern intermittent exotropia, where the eyes drift outward, especially when looking up. Twenty patients received either a standard muscle recession or a recession with an upward shift of th…

This study tested an artificial intelligence platform that screens for cognitive dysfunction by analyzing eye movements. Over 1,500 participants, including people with various dementias and healthy individuals, took part. The AI aims to detect cognitive impairment and provide ref…

This pilot study tested whether special magnifying goggles (Frenzel lenses) and a step-by-step diagnostic algorithm help emergency doctors better detect nystagmus—a telltale eye movement—in patients with sudden vertigo. The goal is to improve diagnosis of stroke versus benign inn…

This study tested two types of eye exercises—gaze stabilization and optokinetic training—in 32 adults aged 35-55 with chronic dizziness from inner ear problems. The goal was to see which better improves dizziness, balance, and confidence in daily activities. Results help guide th…

This study tested whether eye and neck exercises can reduce dizziness and uncontrolled eye movements in young adults with benign paroxysmal positional vertigo (BPPV). Fifty-six participants did either eye exercises alone or combined eye and neck exercises for six weeks. The goal …

This study tested whether giving children a deeper level of muscle relaxation during strabismus (crossed eyes) surgery could prevent a sudden drop in heart rate, known as the oculocardiac reflex. The trial involved 201 children aged 3 to 18 years. Researchers compared two levels …

This trial tested two drugs, propofol and dexmedetomidine, to see which better prevents emergence agitation—a state of restlessness and crying—in children aged 3 to 7 after squint surgery. Eighty children were randomly given one of the drugs after anesthesia. The goal is to find …

This study tested whether gabapentin and memantine can reduce the speed, size, and frequency of involuntary eye movements (nystagmus) in people with oculopalatal tremor, a condition caused by brainstem damage. Seven adults took each drug separately, and researchers measured eye m…

This study tested two drugs, gabapentin and memantine, in 10 people with multiple sclerosis who have a constant eye shaking called pendular nystagmus. The goal was to see if either drug could reduce the eye movement and improve vision and quality of life. Each person tried both d…

This study interviewed 13 parents of children aged 2-6 who had strabismus (crossed eyes) surgery. Researchers wanted to understand how parents gave their children eye drops after surgery and how well the children cooperated. The goal is to learn from these experiences to improve …