Can two common drugs calm uncontrollable eye shaking?
NCT ID NCT02466191
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested whether gabapentin and memantine can reduce the speed, size, and frequency of involuntary eye movements (nystagmus) in people with oculopalatal tremor, a condition caused by brainstem damage. Seven adults took each drug separately, and researchers measured eye movements and vision-related quality of life. The goal was to see if these medications could ease symptoms and improve daily vision.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- gabapentin and memantine
- What this could lead to
- If effective, these drugs could offer a way to reduce involuntary eye movements and improve vision in people with oculopalatal tremor.
- What could go wrong
- This is a very small study (only 7 people) and results may not apply to everyone. It is also an open-label design, which can bias outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospices Civils de Lyon
Lyon, 69002, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.