Ocular motility disease

This study compares two types of special glasses (DIMS and DOT) to control nearsightedness in children aged 6 to 12 who also have intermittent exotropia (a type of eye misalignment). Researchers want to see which lens works better and whether the glasses affect eye coordination. …

This study tests whether 12 sessions of visual therapy (eye exercises) can improve eye alignment and quality of life in people aged 8 to 50 with intermittent horizontal strabismus (eyes that sometimes wander). Participants are randomly assigned to either the therapy group or a no…

This phase 2 trial tests a combination of seven drugs (CL-Pola-R-CHP) in 28 adults aged 65 and older with double or triple-hit diffuse large B-cell lymphoma who are not eligible for transplant. The goal is to see how many patients achieve complete remission after six cycles of tr…

This study compares Botox injections to standard surgery for treating childhood esotropia (crossed eyes) in 244 children. The goal is to see if Botox, a less invasive option, works as well as surgery to straighten the eyes. If successful, it could reduce risks from surgery and an…

This study tests whether injecting Botox into the eye muscles can correct strabismus (misaligned eyes) without surgery. 127 children and adults with small-to-moderate eye turns will receive Botox injections, and their eye alignment will be tracked for a year. The goal is to see i…

This study will check if an AI system can accurately measure eye movements from smartphone videos. About 1,000 adults with suspected eye movement issues will record a short video while following a moving target. The AI's measurements will be compared to expert ratings to see if i…

This study tests whether wearable augmented reality (AR) glasses can diagnose vertigo as accurately as standard eye-movement exams. About 200 adults with vertigo will try both methods during one visit. If successful, AR glasses could make vertigo assessment faster and more access…

This study tests whether watching 3D movies, combined with standard patching therapy, improves depth perception and vision in children aged 4 to 14 with amblyopia (lazy eye). Half the children will receive patching alone, while the other half will also attend weekly 3D movie sess…

This study compares two anesthesia methods for strabismus (eye muscle) surgery in adults: general anesthesia (being fully asleep) versus a combination of sedation with a local numbing injection around the eye. Researchers will measure patient and surgeon satisfaction with each ap…

This study tests whether watching 3D movies can improve depth perception and vision in children aged 4 to 12 who still have some vision loss from lazy eye (amblyopia) despite prior treatment. Forty children will be randomly assigned to watch three movies in either 3D or 2D, then …

This study tests whether patching the stronger eye in the morning (8-10 AM) or evening (5-7 PM) works better for improving vision in children with lazy eye (amblyopia). About 100 children aged 4-8 will wear an eye patch for 2-6 hours daily over 6 months. The goal is to see if tim…

This study explores whether tracking eye movements and arm motions during virtual reality driving tasks can help identify early signs of mild cognitive impairment (MCI) in older adults. Researchers will enroll 192 participants, including healthy young adults, healthy older adults…

This study examines patients who have internuclear ophthalmoplegia, a condition that causes trouble moving the eyes sideways, to see how many later develop multiple sclerosis (MS). Researchers will review medical records of 200 patients to identify factors that predict MS convers…

This study follows 62 people who need a second surgery for crossed or wandering eyes (strabismus). Researchers want to find out what factors increase the risk of needing repeat surgery and how successful the second operation is. Participants get a personalized surgical plan and a…

This study will measure the width of the medial rectus tendon in 28 people having surgery for crossed eyes (esotropia). The goal is to see if tendon width is linked to how much the eye position changes after surgery. If a link is found, it could help surgeons plan more precise op…