Lymphatic system disorder
MONDO:0005833A disease involving the lymphatic part of lymphoid system.
Also known as: disease of lymphatic part of lymphoid system, disease or disorder of lymphatic part of lymphoid system, disorder of lymphatic part of lymphoid system, glands, swollen, lymphatic disease, lymphatic part of lymphoid system disease, lymphatic part of lymphoid system disease or disorder, swollen gland
711 clinical trials for this condition and its sub-types, 31 tagged with Lymphatic system disorder itself.
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Sub-types of Lymphatic system disorder
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Splenic disorder 3 trials · 248 incl. sub-types
8 sub-types
- Spleen neoplasm 0 trials · 232 incl. sub-types Sub-types →
- Hypersplenism 12 trials
- Splenic sequestration 1 trial
- Congestive splenomegaly 0 trials Sub-types →
- Splenic abscess 0 trials
- Splenic infarction 0 trials
- Splenic tuberculosis 0 trials
- Wandering spleen 0 trials
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Lymphedema 145 trials · 205 incl. sub-types
2 sub-types
- Primary lymphedema 9 trials · 66 incl. sub-types Sub-types →
- Elephantiasis 1 trial · 9 incl. sub-types Sub-types →
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Lymph node disorder 0 trials · 84 incl. sub-types
4 sub-types
- Lymph node neoplasm 5 trials · 60 incl. sub-types Sub-types →
- Lymphadenitis 3 trials · 22 incl. sub-types Sub-types →
- Lymph node tuberculosis 3 trials
- Glandular tularemia 0 trials
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Histiocytosis 16 trials · 75 incl. sub-types
5 sub-types
- Langerhans cell histiocytosis 40 trials · 41 incl. sub-types Sub-types →
- Non-Langerhans cell histiocytosis 1 trial · 39 incl. sub-types Sub-types →
- Malignant histiocytosis 3 trials
- ALK+ histiocytosis 0 trials
- Reticulohistiocytic granuloma 0 trials
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Lymphatic system cancer 4 trials · 70 incl. sub-types
4 sub-types
- Lymph node cancer 1 trial · 56 incl. sub-types Sub-types →
- Lymphosarcoma 8 trials
- Spleen cancer 0 trials · 2 incl. sub-types Sub-types →
- Reticulum cell sarcoma 0 trials
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Hemophagocytic syndrome 38 trials · 58 incl. sub-types
2 sub-types
- Secondary hemophagocytic lymphohistiocytosis 15 trials · 24 incl. sub-types Sub-types →
- Hereditary hemophagocytic lymphohistiocytosis 8 trials · 16 incl. sub-types Sub-types →
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Lymphatic vessel neoplasm 0 trials · 15 incl. sub-types
1 sub-type
- Lymphangioma 5 trials · 15 incl. sub-types Sub-types →
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Lymphangiectasis 3 trials
1 sub-type
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Lymphocele 3 trials
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Plastic bronchitis 2 trials
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Pseudolymphoma 2 trials
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Bubonic plague 1 trial
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Lymphogranuloma venereum 1 trial
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Lymphangitis 0 trials
Most studied deeper sub-types
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New pill aims to shrink Hard-to-Treat cancers
Disease control Recruiting nowThis study tests an experimental drug called Tulmimetostat (DZR123) in people with advanced solid tumors or lymphomas that have not improved with standard treatments. The drug is taken as a daily pill, either alone or combined with another drug (enzalutamide) for certain prostate…
Phase 1/2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
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New hope for CLL patients with weak hearts: acalabrutinib under the microscope
Disease control Recruiting nowThis study tests the drug acalabrutinib in people with chronic lymphocytic leukemia (CLL) who also have moderate to severe heart failure. Researchers want to see if acalabrutinib causes fewer heart-related side effects compared to other standard treatments. About 60 adults will t…
Phase 4 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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Unlicensed cord blood units tested for safety in blood cancer patients
Disease control Recruiting nowThis study is testing the safety of using unlicensed umbilical cord blood units for transplants in people with blood cancers or lymphatic diseases. Researchers will monitor for infections and serious reactions after infusion. The goal is to see if these unlicensed units can be a …
Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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New pill combo shows promise for tough brain cancer
Disease control Recruiting nowThis study tests an experimental oral drug called emavusertib (CA-4948), taken alone or with ibrutinib, in adults with relapsed or refractory primary central nervous system lymphoma (PCNSL). The trial has multiple parts to find the safest dose and see if the drug shrinks tumors. …
Phase 1/2 • Sponsor: Curis, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Can a tiny device speed up cancer diagnosis for people with HIV?
Diagnosis Recruiting nowThis study tests new diagnostic approaches for lymphoma and multicentric Castleman disease in people living with HIV who have swollen lymph nodes. Researchers will compare standard biopsies with fine needle aspiration and a new nucleic acid amplification device called TINY. The g…
Sponsor: Indiana University • Aim: Diagnosis
Last updated Aug 30, 2026 00:00 UTC
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New ultrasound technique could spot cancer in lymph nodes without a needle
Diagnosis Recruiting nowThis study tests a new type of ultrasound called super-resolution ultrasound (SRUS) to see if it can better tell the difference between benign (non-cancerous) and malignant (cancerous) swollen lymph nodes. About 779 adults with abnormal lymph nodes will receive an injection of ul…
Sponsor: Peking University Third Hospital • Aim: Diagnosis
Last updated Jun 26, 2026 13:47 UTC
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Massive study launches to unravel mysteries of rare lymphatic diseases
Knowledge-focused Recruiting nowThis natural history study aims to collect data from 1,200 people with lymphatic anomalies—rare conditions affecting the body's lymph system—over many years. Researchers will track symptoms, perform genetic testing, and gather biospecimens to better understand why these condition…
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Aug 08, 2026 00:03 UTC
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Can a headband help your brain take out the trash after a bad Night's sleep?
Knowledge-focused Recruiting nowThis study looks at how sleep helps clean the brain. Researchers will use special MRI scans to see the brain's waste-clearing system in 16 healthy young adults. They will also test a headband that tracks brain waves and uses mild electrical pulses to improve sleep and brain funct…
Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Morning light may heal Veterans' brains after injury
Knowledge-focused Recruiting nowThis study tests whether morning bright light therapy can improve sleep in 300 veterans with traumatic brain injury. Researchers will measure changes in inflammation, energy production in cells, and brain cleaning systems. The goal is to understand how better sleep might support …
Sponsor: Oregon Health and Science University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Scientists map hidden lymphatic highways in Women's arms
Knowledge-focused Recruiting nowThis study uses special imaging to map the lymphatic system in the arms of healthy women and breast cancer survivors who did not develop swelling (lymphedema). The goal is to learn how these alternate pathways work and why some people avoid lymphedema after lymph node removal. Ab…
Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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500-Patient registry aims to unlock better care for rare lymphatic disorders
Knowledge-focused Recruiting nowThis study is a large European registry that will observe up to 500 patients with lymphatic disorders related to congenital heart disease. Researchers will collect data on current diagnostic imaging and treatments like lymphatic embolization to see which approaches improve sympto…
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC