Lymph node disorder

This study looked at whether the HPV vaccine works in girls aged 9 to 17 who are taking medicines that weaken their immune system, such as after an organ transplant or for diseases like lupus. The goal was to see if their bodies produce enough antibodies to protect against HPV. T…

This study looked at whether adding focused radiation (SBRT) or surgery to standard treatments like chemo or hormone therapy helps people with breast cancer that has spread to just one or two places. 129 participants were randomly assigned to get standard care alone or standard c…

This study looked at whether adding a steroid called prednisolone to the usual treatment (immunoglobulin and aspirin) could reduce heart artery damage in children with Kawasaki disease. Over 3,200 children took part. The goal was to see if the combination therapy lowers the chanc…

This study looked at 180 people with rectal cancer that had spread to lymph nodes in the pelvis. One group received a three-drug chemotherapy regimen (FOLFOXIRI) followed by surgery to remove the affected lymph nodes. The other group got standard chemoradiotherapy before surgery.…

This study tested whether injecting the antibiotic gentamicin directly into swollen lymph nodes helps people with cat scratch disease recover faster. 75 participants received either the injection or a placebo, along with standard oral antibiotics. The goal was to see if the injec…

This phase 2 trial tested whether taking iohexol by mouth can treat chylous ascites, a leak of lymphatic fluid that can happen after abdominal or pelvic cancer surgery. The study enrolled 42 patients who developed this condition after surgery. The goal was to see if oral iohexol …

This study tested whether adding the drug axitinib to standard hormone therapy before surgery helps men with prostate cancer that has spread to lymph nodes. About 73 men received either hormone therapy alone or hormone therapy plus axitinib before having their prostate removed. T…

This early-phase study tested a combination of atorvastatin and anakinra in 5 children with Kawasaki disease who had coronary artery abnormalities. The goal was to see if these drugs could safely reduce artery inflammation and prevent future heart problems. The study focused on s…

This study tested a drug called TA-650 in 31 children with Kawasaki disease whose fever did not go away after standard IVIG treatment. The goal was to see if TA-650 could bring down the fever faster and prevent damage to heart arteries compared to another immunoglobulin treatment…

This study tested a new rapid test that checks for thyroid cancer spread to neck lymph nodes in just minutes, instead of the usual days-long wait. Researchers studied 250 adults with suspected or known thyroid cancer, comparing the quick test to standard lab methods. The goal was…

This study tested whether adding two special ultrasound techniques—elastography and contrast-enhanced ultrasound—can better detect breast cancer spread to underarm lymph nodes. Researchers studied 180 women with breast cancer to see if these extra scans improve accuracy compared …

This study tested an artificial intelligence (AI) model designed to detect whether prostate cancer has spread to nearby lymph nodes. Researchers used digital images of lymph node tissue from 225 prostate cancer patients and compared the AI's accuracy to standard pathology reports…

This pilot study tested whether a rapid lab test called frozen section analysis, done during thyroid surgery, can help surgeons decide how many lymph nodes to remove from the neck. The study included 66 adults with low-risk thyroid cancer and no signs of spread before surgery. Th…

This study tested a new ultrasound technique to see the smallest blood vessels in lymph nodes on the neck. Researchers wanted to know if this method could tell the difference between healthy and cancerous lymph nodes. Twenty adults with head and neck cancer, lymphoma, or healthy …

This study looked at the heart health of 61 children who had Kawasaki disease 5 years earlier and were treated with IVIG. Researchers compared them to healthy children using blood tests, blood pressure, artery stiffness, and heart imaging. The goal was to find early signs of hear…

This completed study looked at 289 children to understand what factors increase the risk of serious complications from pharyngitis (sore throat), such as abscesses or severe neck infections. Researchers compared children hospitalized for these complications with those who had pha…

This study tested a program called FinFit to help adolescent and young adult cancer survivors deal with money problems caused by their illness. Researchers interviewed 16 people from community cancer clinics to design and improve the program. The goal was to figure out the best w…

This completed study analyzed data from 1,500 colon cancer patients to see if a new way of classifying lymph node involvement—based on both the number and location of affected nodes and tumor deposits—can better predict survival than the current standard system. Researchers colle…

This study collected blood, saliva, stool, urine, and skin samples from 19 people with unknown or poorly understood immune system problems. The goal was to learn how different parts of the immune system work together. No treatments or drugs were tested. Participants were followed…

This study tested a risk scoring model that predicts whether stomach cancer has spread to nearby lymph nodes before surgery. Researchers looked at data from 120 patients who had their stomach cancer removed. The goal was to see if the model could help doctors make better treatmen…

This study looked at whether the types of bacteria in the gut are linked to whether pancreatic cancer has spread to nearby lymph nodes. Researchers compared stool samples from 55 patients with and without lymph node spread. They hope to find bacterial and chemical clues that coul…

This study looked at 314 patients with small, early-stage papillary thyroid cancer who had surgery to remove half of the thyroid. During the operation, doctors checked nearby lymph nodes for hidden cancer spread. If cancer was found, the rest of the thyroid was removed in the sam…