New drug combo tested to stop prostate cancer spread before surgery
NCT ID NCT01409200
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding the drug axitinib to standard hormone therapy before surgery helps men with prostate cancer that has spread to lymph nodes. About 73 men received either hormone therapy alone or hormone therapy plus axitinib before having their prostate removed. The goal was to see if the combination delays cancer recurrence after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- hormone therapy (androgen deprivation therapy) and axitinib
- What this could lead to
- If successful, this could point toward a more effective pre-surgery treatment for prostate cancer that has spread to lymph nodes.
- What could go wrong
- This is a small, early-phase trial (73 people) with no results yet. Adding axitinib may not improve outcomes and could increase side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
M D Anderson Cancer Center
Houston, Texas, 77030, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New hope for tough prostate cancer: drug cocktails under trial
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