Real-Time tissue test may help surgeons avoid unnecessary neck dissections in thyroid cancer

NCT ID NCT07659717

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This pilot study tested whether a rapid lab test called frozen section analysis, done during thyroid surgery, can help surgeons decide how many lymph nodes to remove from the neck. The study included 66 adults with low-risk thyroid cancer and no signs of spread before surgery. The goal was to see if this approach could reduce unnecessary surgery while still removing enough tissue to control the disease.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Frozen section analysis (a rapid lab test on tissue removed during surgery)
What this could lead to
If successful, this approach could help surgeons tailor the extent of neck surgery in real time, potentially reducing unnecessary procedures and complications.
What could go wrong
This is a small pilot study (66 participants) with no long-term follow-up on cancer recurrence. The findings may not apply to all thyroid cancer patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Policlinico "P. Giaccone" University of Palermo

    Palermo, Sicily, 90127, Italy

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