Ischemic disease

This study tests whether using real-time measurements of oxygen levels in the brain and carbon dioxide in the breath can guide CPR more effectively than standard audiovisual feedback. Adults who have a cardiac arrest in the hospital and need CPR for at least five minutes may join…

This study tested whether using sevoflurane gas for anesthesia during kidney transplant surgery helps the new kidney recover faster than standard propofol anesthesia. 120 adults receiving a kidney transplant were randomly assigned to one of the two anesthetics. Researchers tracke…

This study tested whether a non-invasive procedure called remote ischemic preconditioning (RIC) could improve blood flow and reduce tissue damage in women undergoing breast reconstruction with a free flap. RIC involves using a blood pressure cuff on the upper arm to create short …

This study tested whether the drug Mexidol (given first as injections, then as pills) can improve thinking and memory in people with chronic cerebral ischemia, a condition where the brain doesn't get enough blood flow. 318 adults aged 40-90 with mild to moderate cognitive impairm…

This study tested whether injecting donor stem cells into the leg muscles before amputation could prevent wound problems and reduce the need for more amputations. 81 people scheduled for leg amputation due to poor blood flow took part. The main goal was to check safety, not yet t…

This study tested whether adding art therapy to standard speech rehab could help people who recently had a stroke and now have trouble speaking (aphasia). Fifteen participants received 12 art therapy sessions alongside their usual therapy. Researchers used brain scans to see if a…

This study tested a therapy called cognitive multi-sensory rehabilitation (CMR) in 40 people who had a stroke 6 to 18 months earlier. The therapy uses movement awareness and discrimination exercises to help the brain and arm work together. Participants received 12 sessions over f…

Children can break the upper arm bone just above the elbow, and sometimes the break presses on blood vessels so the wrist pulse disappears. Doctors disagree about when to operate on those vessels and when to wait. This study follows 190 children up to age 15 at pediatric surgery …

This study looked at how blood moves through leg muscles in people who have had a stroke compared to healthy adults. Researchers used gentle leg movements and muscle contractions to measure blood flow. The goal was to learn more about why stroke survivors often have reduced exerc…

This study adapted several questionnaires that measure arm and hand function after a stroke into Polish, and checked how reliable and accurate they are. One hundred people who had an ischemic stroke at least six months ago took part. The goal was to give Polish-speaking patients …

This study looked at 191 women with non-obstructive coronary artery disease (plaque that doesn't block arteries). Researchers used CT scans to measure whether intensive medical therapy (like statins and blood pressure drugs) reduced plaque more than usual care. The goal was to se…

This study tests a motorized tilt table and lower-body pressure chamber designed to help military pilots train for and understand fainting and blood pooling. Forty-six pilots and cadets will be tilted and exposed to pressure changes while their heart rate, blood pressure, and bra…

This study measured the amount of common blood thinners (dabigatran, apixaban, and rivaroxaban) in the blood of 308 Chinese adults with atrial fibrillation who had been taking the medication for at least 3 months. The goal was to establish normal reference ranges for these drugs …

This completed study looked at 30 patients with septic shock in the ICU. Researchers wanted to see how high doses of the drug norepinephrine affect not just large blood vessels, but also tiny ones (microcirculation). They used a non-invasive light-based device to measure oxygen l…

This study looked at the records of 2500 adults admitted to the hospital with serious belly problems like blockages or infections. The goal was to compare outcomes for different treatments, including surgery, keyhole surgery, radiology procedures, and comfort care. By grouping pa…