Anesthesia choice may boost kidney transplant success

NCT ID NCT00337051

Completed Disease control Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether using sevoflurane gas for anesthesia during kidney transplant surgery helps the new kidney recover faster than standard propofol anesthesia. 120 adults receiving a kidney transplant were randomly assigned to one of the two anesthetics. Researchers tracked kidney function for a year after surgery to see if sevoflurane reduced damage from the blood flow interruption that occurs during transplant.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Sevoflurane (an inhaled anesthetic gas)
What this could lead to: If it works, this could show that choosing sevoflurane during surgery helps transplanted kidneys start working sooner, reducing the need for dialysis after transplant.
What could go wrong: This is a completed Phase 3 trial, but results are not yet widely confirmed. The benefit may be small or not apply to all transplant patients. Anesthesia risks like allergic reactions or rare malignant hyperthermia exist.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute kidney injury chronic kidney disease end stage renal failure ischemic disease kidney failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

END-STAGE CHRONIC RENAL DISEASE RENAL TRANSPLANTATION SEVERE ACUTE KIDNEY FAILURE

Contacts and locations

Locations

Département d'anesthésie réanimation 1 - Hôpital Pellegrin - CHU de Bordeaux

Bordeaux, 33076, France

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