Hyperostosis

This study looks at whether treating an extra nerve in the foot can improve pain relief for people with long-term heel pain. About 48 adults will receive a standard nerve treatment, with half also getting treatment on a second nerve. Researchers will measure pain and foot functio…

This study tests whether low-dose radiation therapy can ease pain and improve daily life for people with heel spurs and plantar fasciitis. About 35 adults who have had pain for at least 3 months will receive the treatment. Researchers will measure pain, function, and quality of l…

This study is testing whether a lower dose of radiation can relieve pain from heel spurs just as well as the standard dose. About 366 adults with chronic heel pain that hasn't improved with other treatments will receive one of three radiation schedules. The goal is to find a gent…

This study follows adults with melorheostosis, a rare disease that causes bone thickening, pain, and joint problems. Researchers will track how the disease progresses over time, collect genetic samples from patients and their relatives, and look for biomarkers. The goal is to bet…

This study reviews the medical records of 300 people with multiple osteochondromas (a rare bone condition causing multiple bony growths) who had surgery at a specialized hospital in Italy. Researchers want to understand how many surgeries patients typically need, what types of su…

This study is testing whether a standard deep-cleaning procedure for gum disease (scaling and root planing) changes the levels of three specific proteins in saliva. The researchers will compare these changes between smokers and non-smokers with moderate to advanced gum disease. A…

This study aims to find the genes and genetic changes that cause craniometaphyseal dysplasia (CMD), a rare disorder that leads to abnormal bone growth in the skull and other bones. Researchers will analyze blood and tissue samples from 600 people, including affected individuals a…

This study looks at how multiple osteochondromas (non-cancerous bone growths) affect movement and body shape in children and adults. Researchers will use wearable sensors, pressure mats, and 3D body scans to measure walking, balance, and joint motion. The goal is to find simple w…

This study is building a large registry of people with multiple osteochondromas, a condition that causes benign bone tumors. Researchers will collect medical history, genetic data, and treatment information from up to 10,000 participants. The goal is to better understand the dise…