Hyperostosis

This study compares two types of spinal fusion cages used in back surgery: a new titanium cage with a special rough surface and a standard plastic cage. About 100 adults with spine problems like narrowing of the spinal canal or slipped vertebrae will be randomly assigned to recei…

This study follows people who carry a gene mutation that puts them at high risk for Paget's disease of the bone. They previously received either zoledronic acid or a placebo in the ZiPP trial. Now researchers will track them for another 5 years to see if the drug can prevent or d…

This small pilot study is testing whether using heat (radiofrequency ablation) to disable a nerve in the heel can relieve chronic pain from plantar fasciitis or heel spurs. The 31 participants have had pain for over 6 months and tried at least four other treatments without succes…

This study compares two treatments for plantar fasciitis, a common cause of heel pain. One group will receive shockwave therapy, a costly procedure, while the other will get myofascial release, a hands-on massage technique. Researchers want to see if the cheaper option works just…

This study looks at whether a genetic test can predict who will develop Paget's disease of the bone, a condition that can cause pain, deformity, and hearing loss. Researchers are studying 135 people aged 45 and older who have a parent or sibling with Paget's but do not have the d…