Hyperostosis
MONDO:0002185Excessive thickening of bone.
Also known as: bone hypertrophy, hypertrophy of bone, hypertrophy of bone (morphologic abnormality)
58 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Spine surgery showdown: new titanium cage may fuse bones faster
Disease control OngoingThis study compares two types of spinal fusion cages used in back surgery: a new titanium cage with a special rough surface and a standard plastic cage. About 100 adults with spine problems like narrowing of the spinal canal or slipped vertebrae will be randomly assigned to recei…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Bone drug may stop Paget's before it starts in at-risk families
Prevention ENROLLING_BY_INVITATIONThis study follows people who carry a gene mutation that puts them at high risk for Paget's disease of the bone. They previously received either zoledronic acid or a placebo in the ZiPP trial. Now researchers will track them for another 5 years to see if the drug can prevent or d…
Sponsor: University of Edinburgh • Aim: Prevention
Last updated Jun 27, 2026 09:06 UTC
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Zapping a heel nerve: new hope for chronic foot pain?
Symptom relief OngoingThis small pilot study is testing whether using heat (radiofrequency ablation) to disable a nerve in the heel can relieve chronic pain from plantar fasciitis or heel spurs. The 31 participants have had pain for over 6 months and tried at least four other treatments without succes…
Phase: NA • Sponsor: Şahide Eda Artuç • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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Heel pain showdown: cheap massage vs. pricey shockwave – which works better?
Symptom relief ENROLLING_BY_INVITATIONThis study compares two treatments for plantar fasciitis, a common cause of heel pain. One group will receive shockwave therapy, a costly procedure, while the other will get myofascial release, a hands-on massage technique. Researchers want to see if the cheaper option works just…
Phase: NA • Sponsor: Istanbul Rumeli University • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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New study aims to predict Paget's disease before it strikes
Knowledge-focused OngoingThis study looks at whether a genetic test can predict who will develop Paget's disease of the bone, a condition that can cause pain, deformity, and hearing loss. Researchers are studying 135 people aged 45 and older who have a parent or sibling with Paget's but do not have the d…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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Weekly Check-Ins could boost patient satisfaction for chronic pain
Knowledge-focused TerminatedThis study looked at whether having more frequent contact with a clinician (at least once a week) improves satisfaction for people with long-lasting musculoskeletal conditions. Participants were split into two groups: one with standard contact and one with extra check-ins via tex…
Phase: NA • Sponsor: University of Texas at Austin • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Can a special clinic get workers back on the job faster? norway launches massive study.
Knowledge-focused OngoingThis study tests whether a Norwegian clinic (NSAC) helps people with common mental health issues or muscle pain return to work sooner. 2500 adults are split into three groups: one gets treatment quickly, one waits 10-14 weeks, and one gets a basic check-up. Researchers will track…
Phase: NA • Sponsor: Nordlandssykehuset HF • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Massive PT study mines 4 million records to find what works best
Knowledge-focused OngoingThis study looks back at the medical records of about 4 million people who had physical or occupational therapy for muscle and joint problems. Researchers want to see if different ways of giving therapy lead to different results. No new treatments are tested—the goal is to learn …
Sponsor: ATI Holdings, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Phone app vs. doctor: can a mobile tool catch infections after surgery?
Knowledge-focused TerminatedThis study aimed to see if a mobile monitoring tool could accurately identify surgical site infections (SSIs) in orthopedic surgery patients, compared to the usual manual review. The study was withdrawn before enrolling any participants, so no results are available. It was design…
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC