Hyperostosis corticalis generalisata

Hyperostosis corticalis generalisata, also known as van Buchem disease, is a rare craniotubular hyperostosis characterized by hyperostosis of the skull, mandible, clavicles, ribs and diaphyses of the long bones, as well as the tubular bones of the hands and feet. Clinical manifestations include increased skull thickness with cranial nerve entrapment causing inconsistent cranial nerve palsies.

Also known as: Van Buchem disease, endosteal hyperostosis, hyperostosis corticalis generalisata, hyperphosphatasemia tarda, van Buchem disease, van Buchem disease type 1, SOST-related sclerosing bone dysplasia, VAN Buchem disease

0 clinical trials for this condition and its sub-types.