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Hiatus hernia
MONDO:0007721Herniation of the upper part of the stomach through the diaphragm.
Also known as: hiatal hernia, hiatus hernia, hiatus hernia (disease), hernia, hiatus
49 clinical trials for this condition and its sub-types.
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Broader categories
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Keyhole surgery offers relief for hidden hiatal hernia sufferers
Disease control CompletedThis study looked at whether a specific keyhole surgery (Toupet fundoplication) can help people with a hiatal hernia that causes heartburn but doesn't show up on X-rays. 100 adults with this condition had the surgery and were followed to see if their symptoms came back or if they…
Phase: NA • Sponsor: Minia University • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New collagen mesh could reduce hernia surgery risks
Disease control CompletedThis study tested a special collagen mesh for hernia repair in 30 patients who were at high risk for complications, such as those with diabetes or infections. The mesh is designed to be absorbed by the body and help tissue heal naturally, avoiding problems linked to permanent syn…
Phase: NA • Sponsor: Adichunchanagiri Institute of Medical Sciences, B G Nagara • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New mesh shows promise for fixing stomach hernias
Disease control CompletedThis small pilot study tested a biological mesh called SurgiMend during laparoscopic hiatal hernia repair in 9 adults. The goal was to see if the mesh helps prevent the hernia from coming back and improves quality of life. Participants were followed for 6 months with X-rays and s…
Phase: NA • Sponsor: Kettering Health Network • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Mesh repair during sleeve gastrectomy may slash hernia return
Disease control CompletedThis study looked at 20 adults who had weight-loss surgery (sleeve gastrectomy) and also needed hiatal hernia repair. Surgeons used a mesh to strengthen the hernia fix. The goal was to see if this lowers the chance of the hernia coming back. Results suggest mesh repair may help c…
Phase: NA • Sponsor: Zagazig University • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Which mesh placement is safer for hernia repair? new trial investigates
Disease control CompletedThis completed trial compared two surgical techniques for repairing incisional hernias: placing mesh on top of the abdominal muscle (onlay) versus behind it (sublay). 350 adults were randomly assigned to one of the two procedures and followed for three months. The goal was to see…
Phase: NA • Sponsor: Hayat Abad Medical Complex, Peshawar • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Simple drug may cut infection risk after major gut surgery
Disease control CompletedThis study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of infection after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if the drug reduces surgical site infections compared to a …
Phase: PHASE4 • Sponsor: Bayside Health • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New study tests IV lidocaine for easier hernia recovery
Symptom relief CompletedThis study tests whether giving IV lidocaine during paraesophageal hernia surgery can reduce pain and speed recovery. About 50 adults having elective laparoscopic hernia repair will receive either lidocaine or a placebo alongside standard pain management. Researchers will measure…
Phase: PHASE4 • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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Physical therapy after hernia surgery shows promise in small trial
Symptom relief CompletedThis study looked at whether a special physical therapy program for the core muscles could help people recover after surgery for a ventral hernia. 138 adults who were scheduled for hernia repair took part. The main goal was to see if the therapy improved their mobility and physic…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Can an online wellness program ease anxiety in chronic disease?
Symptom relief CompletedThis study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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New anesthesia combo could slash opioid use after hernia surgery
Symptom relief CompletedThis study tested whether a special anesthesia plan using dexmedetomidine and ketamine could reduce the need for opioid painkillers after laparoscopic hiatal hernia repair. Fifty adults having elective surgery were randomly assigned to receive either the opioid-sparing protocol o…
Phase: NA • Sponsor: Endeavor Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Simple relaxation exercises may ease back pain and fear of movement
Symptom relief CompletedThis study looked at whether progressive relaxation exercises can help people with lumbar disc herniation (a slipped disc in the lower back) feel less afraid of moving, have less pain, and enjoy a better quality of life. About 96 adults with confirmed slipped discs were randomly …
Phase: NA • Sponsor: Hasan Kalyoncu University • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Lavender or pressure points: Drug-Free pain relief for kids after surgery?
Symptom relief CompletedThis study tested whether aromatherapy (breathing lavender oil) or acupressure (gentle thumb pressure on specific points) could reduce pain and improve sleep in 100 children aged 6-12 after abdominal surgeries like appendix or hernia repair. The goal was to find simple, non-drug …
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Jun 26, 2026 14:18 UTC
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Emergency hernia care under the microscope: what works best?
Knowledge-focused CompletedThis study followed 280 adults who came to the hospital with a painful hernia needing urgent care. Researchers wanted to see how doctors decide between surgery and non-surgical management, and how patients fared afterward. The goal is to gather real-world data to improve future t…
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Could a stomach problem harm your lungs? new study investigates
Knowledge-focused CompletedThis completed study from the University of Virginia looked at whether having a hiatal hernia (a stomach issue) is linked to early, undetected lung scarring. Researchers collected blood and lung fluid samples from 14 adults before surgery to measure signs of lung injury. The goal…
Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Botox before belly surgery: breathing breakthrough?
Knowledge-focused CompletedThis study looked at whether injecting botulinum toxin (Botox) into the side belly muscles before large hernia repair surgery can improve breathing. Large hernias can push organs out of place, making surgery tricky and affecting lung function. The study measured lung capacity in …
Sponsor: Swissmed Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Does your anesthesia choice affect pain after hernia surgery?
Knowledge-focused CompletedThis study looked at whether the type of anesthesia used during hernia surgery affects pain levels afterward. Ten men having hernia repair were randomly assigned to receive either intravenous propofol or inhaled sevoflurane. Researchers measured pain right after surgery and over …
Phase: PHASE4 • Sponsor: VA Pittsburgh Healthcare System • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Which position is best for a rectal exam? study seeks answer
Knowledge-focused CompletedThis study compared two common positions for a digital rectal exam: lying on your side (lateral decubitus) versus lying on your back (supine). The goal was to see which position allows doctors to perform a more complete exam. The study involved 320 men with conditions like colon …
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:17 UTC