Which mesh placement is safer for hernia repair? new trial investigates

NCT ID NCT07401446

Completed Disease control Sponsor: Hayat Abad Medical Complex, Peshawar Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This completed trial compared two surgical techniques for repairing incisional hernias: placing mesh on top of the abdominal muscle (onlay) versus behind it (sublay). 350 adults were randomly assigned to one of the two procedures and followed for three months. The goal was to see which method leads to fewer complications like infection, fluid buildup, or hernia recurrence.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: polypropylene mesh
What this could lead to: If one method proves safer, it could become the preferred surgical approach for incisional hernia repair, reducing complications like infection and recurrence.
What could go wrong: This is a single-center trial with short follow-up (3 months), so results may not apply to all patients or predict long-term outcomes. Individual surgeon skill may also affect results.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Hernia Hernia, Abdominal hiatus hernia Incisional Hernia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ABDOMINAL WALL HERNIA HERNIA INCISIONAL HERNIA REPAIR SYNTHETIC MESH VENTRAL HERNIA REPAIR

Contacts and locations

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Locations

Hayatabad Medical Complex

Peshawar, KPK, 25000, Pakistan

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