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Frozen shoulder
MONDO:0006763A painful inflammatory process leads to a mechanical block in active and passive range of motion (ROM) of the shoulder. Adhesive capsulitis of the shoulder is characterized by functional loss of passive and active shoulder motion. This inflammatory process results in fibroblastic proliferation and extensive scar tissue formation. Fibroblastic proliferation, a late phase of the inflammatory process involved in tissue repair, leads to thickening, fibrosis, and adhesion of the capsule to itself and the humerus.
Also known as: adhesive capsulitis, adhesive capsulitis of shoulder
129 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New device could help surgeons spot brain tumors instantly
Diagnosis Not yet recruitingThis study tests a new imaging device called cCeLL that uses a fluorescent dye to help surgeons see brain tumor tissue in real time during surgery. Thirty adults with suspected brain tumors will have their tumor tissue examined both by the device and by standard lab analysis. The…
Phase: PHASE1 • Sponsor: VPIX Medical • Aim: Diagnosis
Last updated Jun 27, 2026 08:00 UTC
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New pill aims to shield stomachs from common painkiller damage
Prevention Not yet recruitingThis study tests whether a new medicine called Fexuprazan (Fexuclue) can prevent stomach ulcers caused by NSAID painkillers like ibuprofen. About 360 adults with joint or muscle pain who need daily NSAIDs will take either Fexuprazan or an older drug (Lansoprazole) for 24 weeks. T…
Phase: PHASE4 • Sponsor: Daewoong Pharmaceutical Co. LTD. • Aim: Prevention
Last updated Jun 27, 2026 12:07 UTC
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Could a nerve block boost frozen shoulder treatment?
Symptom relief Not yet recruitingThis study compares two treatments for frozen shoulder (retractile capsulitis): a standard steroid injection into the shoulder joint versus that same injection plus a nerve block near the shoulder blade. The nerve block uses a numbing medicine and a steroid to calm the nerve that…
Phase: PHASE2 • Sponsor: Nantes University Hospital • Aim: Symptom relief
Last updated Jul 04, 2026 00:00 UTC
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Simple shoulder exercises may ease frozen shoulder pain
Symptom relief Not yet recruitingThis study tests if deltoid strengthening exercises can reduce pain and improve movement in people with frozen shoulder (adhesive capsulitis). 48 adults aged 40-60 with stage II or III frozen shoulder will do specific isometric exercises targeting the deltoid muscle. Researchers …
Phase: NA • Sponsor: Riphah International University • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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Hands-On healing: new study tests OMT for frozen shoulder relief
Symptom relief Not yet recruitingThis study tests whether adding Osteopathic Manipulative Treatment (OMT) — a non-invasive, hands-on therapy — to standard care helps people with frozen shoulder recover faster and feel more satisfied. About 300 adults who have not yet been treated for frozen shoulder will be assi…
Phase: PHASE4 • Sponsor: University Hospitals Cleveland Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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New shoulder block offers hope for chronic pain sufferers
Symptom relief Not yet recruitingThis study tests a new type of nerve block (PENG block) for people with chronic shoulder pain that hasn't improved with other treatments. 45 adults will get an ultrasound-guided injection of numbing medicine and steroid. Researchers will measure pain, shoulder function, and satis…
Phase: NA • Sponsor: Ankara City Hospital Bilkent • Aim: Symptom relief
Last updated Jun 27, 2026 12:38 UTC
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Could a home device ease frozen shoulder pain?
Symptom relief Not yet recruitingThis study looks at whether using a home-based electrical stimulation device, along with standard physical therapy, can help reduce pain and improve shoulder function in people with frozen shoulder. Ten adults diagnosed with the condition will use the device at home while continu…
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Frozen shoulder patients may get relief by working out the other arm
Symptom relief Not yet recruitingThis study tests whether cross training—exercising the healthy arm—can improve pain, function, and mobility in people with frozen shoulder, without directly working the painful shoulder. About 38 adults aged 18-65 with unilateral frozen shoulder will be randomly assigned to stand…
Sponsor: Inonu University • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Could a simple pill boost knee replacement recovery?
Symptom relief Not yet recruitingThis study tests whether taking tranexamic acid pills for a week after knee replacement surgery helps people recover better. 350 adults having their first knee replacement will receive either the drug or a placebo. Researchers will track pain, stiffness, and function for up to 2 …
Phase: NA • Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Frozen shoulder showdown: which treatment wins?
Symptom relief Not yet recruitingThis study compares two common treatments for frozen shoulder (adhesive capsulitis): a procedure that stretches the shoulder joint capsule (capsular distension) and a steroid injection. Both are followed by a rehab program. The trial will measure pain, movement, and disability in…
Phase: NA • Sponsor: Faculty of Medicine of Tunis • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Robot arm could help unfreeze stiff shoulders
Symptom relief Not yet recruitingThis study tests whether a robotic arm exoskeleton can help people with frozen shoulder move better and feel less pain. About 40 adults with stiff-phase frozen shoulder will use the robot for assisted exercises. The goal is to see if the robot improves shoulder range of motion an…
Phase: NA • Sponsor: China Medical University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Simple mobility training may ease frozen shoulder pain
Symptom relief Not yet recruitingThis study looks at whether adding neck and upper back mobility exercises to standard care can improve posture, reduce shoulder pain, and increase range of motion in people with frozen shoulder. Researchers will enroll 40 adults aged 20 to 70 who have been diagnosed with frozen s…
Phase: NA • Sponsor: Zonguldak Bulent Ecevit University • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Can your own blood and fat heal aching joints? new trial aims to find out
Symptom relief Not yet recruitingThis early-phase trial will test four orthobiologic treatments—PRP, bone marrow concentrate, hyaluronic acid, and nanofat—in 300 adults with various muscle, joint, tendon, or bone conditions. The goal is to see if these natural substances can reduce pain and improve joint functio…
Phase: EARLY_PHASE1 • Sponsor: PROREGEN • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Virtual reality could ease stubborn shoulder pain at home
Symptom relief Not yet recruitingThis study tests whether a home-based virtual reality (VR) exercise program is practical and helpful for people with shoulder pain lasting more than three months. Thirty adults aged 16 and older with rotator cuff syndrome, frozen shoulder, or shoulder instability will use a VR he…
Phase: NA • Sponsor: HAN University of Applied Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Nerve block before shoulder injection may ease frozen shoulder pain
Symptom relief Not yet recruitingFrozen shoulder causes pain and stiffness. A common treatment called hydrodistension injects fluid into the shoulder joint to stretch it, but it can be painful. This study tests whether giving a nerve block first can reduce that pain and improve results. Fifty adults with frozen …
Phase: NA • Sponsor: Universidade do Porto • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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New combo therapy could thaw frozen shoulders faster
Symptom relief Not yet recruitingThis study tests whether combining two manual therapy techniques—Mulligan mobilization and scapular mobilization—can improve shoulder movement and reduce pain in people with frozen shoulder better than standard physiotherapy. Thirty-eight adults aged 30 to 60 with unilateral froz…
Phase: NA • Sponsor: Deraya University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Shock wave therapy tested for stubborn frozen shoulder pain
Symptom relief Not yet recruitingThis study explores whether a non-invasive treatment called extracorporeal shock wave therapy (ESWT) can reduce pain and improve shoulder movement in people with chronic adhesive capsulitis (frozen shoulder) who haven't gotten better with standard physiotherapy. Researchers will …
Phase: NA • Sponsor: University of Stirling • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Phone app may boost exercise for aching joints
Symptom relief Not yet recruitingThis study looks at whether a mobile app can help people with common pains (neck, shoulder, back, or knee) do their prescribed home exercises more regularly. About 30 adults will be split into two groups: one using the app and one doing traditional exercises. The goal is to see i…
Phase: NA • Sponsor: National Yang Ming Chiao Tung University • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Frozen shoulder breakthrough? new combo therapy aims to restore movement
Symptom relief Not yet recruitingThis study looks at whether adding nerve-stretching exercises to standard capsule-stretching exercises can improve shoulder movement in people with frozen shoulder (adhesive capsulitis). About 50 adults aged 40–70 with moderate-to-severe frozen shoulder will be split into two gro…
Phase: NA • Sponsor: Prince Sattam Bin Abdulaziz University • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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New exercise combo may ease frozen shoulder pain
Symptom relief Not yet recruitingThis study tests whether adding pectoralis minor stretching and strengthening to standard mobility and stability exercises can better reduce shoulder pain and improve movement in people with frozen shoulder (adhesive capsulitis). About 70 adults aged 40-70 will be randomly assign…
Phase: NA • Sponsor: Lahore University of Biological and Applied Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Laser or muscle work: which eases frozen shoulder in diabetes?
Symptom relief Not yet recruitingThis study tests whether low-level laser therapy or muscle energy techniques work better for reducing pain and improving shoulder movement in people with type 2 diabetes who have frozen shoulder. Thirty-six adults aged 18 to 65 will receive one of the two treatments plus standard…
Phase: NA • Sponsor: University of Lahore • Aim: Symptom relief
Last updated Jun 26, 2026 18:43 UTC
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Can a gentle touch unfreeze shoulders? new trial tests fascial therapy
Symptom relief Not yet recruitingThis study tests whether adding fascial therapy (a type of hands-on tissue manipulation) to standard electrotherapy can improve pain, movement, and joint awareness in people with frozen shoulder. Thirty-six adults aged 35-60 will be split into two groups: one gets only electrothe…
Phase: NA • Sponsor: Hasan Kalyoncu University • Aim: Symptom relief
Last updated Jun 26, 2026 14:42 UTC
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Simple exercises may ease frozen shoulder pain, new study hopes to prove
Symptom relief Not yet recruitingThis study will test whether adding exercise training to standard electrotherapy (heat, TENS, ultrasound) helps people with frozen shoulder (adhesive capsulitis) more than electrotherapy alone. Thirty-two adults aged 35-60 will be split into two groups and treated for 3 weeks. Re…
Phase: NA • Sponsor: Hasan Kalyoncu University • Aim: Symptom relief
Last updated Jun 26, 2026 13:52 UTC
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New urdu tool could help millions with muscle and joint pain
Knowledge-focused Not yet recruitingThis study aims to translate and adapt a widely used questionnaire for musculoskeletal problems into Urdu. Researchers will enroll 110 Urdu-speaking adults, including patients with muscle or joint issues and healthy volunteers. The goal is to create a validated tool to measure sy…
Sponsor: Riphah International University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Could menopause and blood sugar be tied to frozen shoulder? new study aims to find out
Knowledge-focused Not yet recruitingThis study will explore if menopause and blood sugar levels are linked to frozen shoulder in women. Researchers will survey women who have had frozen shoulder and closely monitor a smaller group of perimenopausal women with and without the condition. The goal is to understand why…
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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AI vs. doctor: which note do patients trust more?
Knowledge-focused Not yet recruitingThis study looks at how patients feel when reading their own medical notes. Some will read the original doctor's note, others will read a simpler version written by artificial intelligence. Researchers want to see if the AI summary changes how much patients trust their doctor or …
Phase: NA • Sponsor: University of Texas at Austin • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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New study eyes Tirzepatide's hidden impact on joints and heart
Knowledge-focused Not yet recruitingThis observational study in Mexico will follow 30 adults already taking tirzepatide for conditions like diabetes or obesity. Researchers will use MRI scans of the knees, CT scans of the heart, and body composition tests to see how the drug affects cartilage, heart fat, and overal…
Sponsor: JULIO GRANADOS MONTIEL • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Hip replacement patients monitored for years to improve future surgeries
Knowledge-focused Not yet recruitingThis study will follow 200 people who have had a complex or revision hip replacement at University Hospitals Leuven. The goal is to track how many need another surgery and why, and to improve care by learning from real-world results. No new treatment is being tested—this is an ob…
Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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New digital tool aims to speed up return to work for those with muscle pain
Knowledge-focused Not yet recruitingThis study tests a decision support system called SmaRTWork to help people on sick leave due to muscle or back pain return to work. About 298 adults in Norway will either use the system or receive usual care. The main goal is to see if the tool helps them return to work sustainab…
Phase: NA • Sponsor: Norwegian University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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New tech measures arm precision in shoulder patients
Knowledge-focused Not yet recruitingThis study will test a system called AuReha to see how well it measures arm movement precision in people with shoulder issues like instability or stiffness. About 52 adults will do exercises with both their healthy and affected arms, and the system will track movement accuracy, t…
Phase: NA • Sponsor: DigitalRehab • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC