Fetal alcohol syndrome
MONDO:0016011Fetal alcohol syndrome (FAS) is a rare malformation syndrome caused by excessive maternal consumption of alcohol during pregnancy. It is characterized by prenatal and/or postnatal growth deficiency (weight and/or height <10th percentile), a unique cluster of minor facial anomalies (short palpebral fissures, flat and smooth philtrum, and thin upper lip) and severe central nervous system (CNS) abnormalities including microcephaly, and cognitive and behavioral impairment (intellectual disability, deficit in general cognition, learning and language, executive function, visual-spatial processing, memory, and attention).
Also known as: FASD, fetal alcohol spectrum disorders, foetal alcohol spectrum disorders, ARBD, ARND, FAS, alcohol-related neurodevelopmental disorder, alcohol-related birth defects
107 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
Jobs for sobriety: VA tests work programs to beat addiction
Disease control OngoingThis study tests whether referring Veterans in early recovery from substance use disorder to work-focused programs (like supported employment) helps them stay sober and function better. About 100 Veterans will be randomly assigned to get the work referral or usual treatment alone…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
-
Telehealth counseling may break down barriers to opioid treatment for veterans
Disease control OngoingThis study tests whether a telehealth-delivered counseling program, called VetReach, can help veterans with opioid use disorder engage in treatment and improve their outcomes. The program combines motivational interviewing and cognitive behavioral therapy, delivered remotely. Res…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
-
New program aims to curb drug use in rural parents by tackling social needs
Disease control OngoingThis study tests a program called Just Care for Families, designed to help parents in rural Oregon who are involved with child welfare services and struggle with opioid or methamphetamine use. The program combines substance use treatment, mental health support, parenting training…
Phase: NA • Sponsor: Chestnut Health Systems • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
-
ER chat could curb substance use: 650-Person trial launches
Disease control ENROLLING_BY_INVITATIONThis study tests whether a brief screening and a telehealth counseling session in the emergency department can help people reduce their use of drugs or alcohol. About 650 adults who are at low or moderate risk for substance use problems will take part. The goal is to see if this …
Phase: NA • Sponsor: Purdue University • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
-
VA tests new combo therapy to help veterans beat addiction
Disease control OngoingThis study looks at whether adding a six-session group recovery program and a 90-day home telehealth program can help veterans with substance use disorders drink less and use fewer drugs. About 195 veterans from a VA psychiatric unit will be randomly assigned to one of three grou…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC
-
Could a common nutrient boost brain power in children exposed to alcohol before birth?
Disease control OngoingThis study tests whether choline, a vitamin-like nutrient, can improve memory, thinking, and behavior in children aged 2.5 to 5 years with Fetal Alcohol Spectrum Disorders (FASD). Participants receive choline daily for either 3 or 6 months. Researchers measure changes in memory, …
Phase: PHASE2 • Sponsor: Jeff Wozniak • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
-
FASD study pulled before it began: oxygen vs. brain games never tested
Disease control TerminatedThis study was designed to see if hyperbaric oxygen therapy or computerized cognitive training could help adults with Fetal Alcohol Spectrum Disorder (FASD) think and function better. It planned to enroll 0 participants and was withdrawn before starting, so no results are availab…
Phase: NA • Sponsor: Assaf-Harofeh Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
-
New study tests Team-Based approach to curb overdose risk
Disease control OngoingThis study compares two ways to help people with both substance use and mental health disorders: a full team-based program called MISSION that provides counseling, peer support, and community outreach for 6 months, versus just linking them with a peer specialist. Researchers hope…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
-
Peer power: new study tests whether support buddies boost HIV and mental health care
Disease control OngoingThis study looks at whether having a trained peer (someone with similar experiences) as a case manager can help people with HIV who also have mental health or substance use problems get the care they need. About 405 adults from an HIV clinic will be randomly assigned to either us…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
-
French cities launch community push to wipe out hepatitis c in drug users
Disease control OngoingThis study aims to eliminate hepatitis C among people who use drugs in Paris, Marseille, Lyon, and Fort-de-France. Researchers will screen participants, provide immediate treatment, and use a peer-referral system to reach more people. The goal is to see if this community-based ap…
Phase: NA • Sponsor: ANRS, Emerging Infectious Diseases • Aim: Disease control
Last updated Jun 26, 2026 14:26 UTC
-
Does rehab rebuild empathy? a trial puts social skills to the test.
Symptom relief OngoingThis study asks whether standard residential treatment for substance use disorders can improve a person's ability to empathize with others. Researchers will measure empathy levels in about 108 adults before and after they complete a residential program followed by partial hospita…
Sponsor: Nova Southeastern University • Aim: Symptom relief
Last updated Jul 24, 2026 00:00 UTC
-
Can a Dog's companionship bring lasting social gains for children with FASD?
Symptom relief OngoingThis study follows children and adolescents with fetal alcohol spectrum disorder (FASD) who have already completed a dog-assisted therapy program. Researchers want to see if improvements in social skills, behavior, emotional well-being, and quality of life persist over 12 months.…
Phase: NA • Sponsor: Hospital Universitari Vall d'Hebron Research Institute • Aim: Symptom relief
Last updated Jul 23, 2026 00:00 UTC
-
New program aims to boost Veterans' social and physical health
Symptom relief OngoingThis study tests a program called Omnis Salutis for recent veterans with PTSD, depression, anxiety, or substance use disorders. The program teaches veterans to identify their health goals and communicate them to doctors and family. Researchers want to see if it improves social an…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
-
Can acting out help heal? drama therapy trial targets dual diagnosis
Symptom relief TerminatedThis pilot study tests a specific type of drama therapy for people who have both a mental health condition (like depression or bipolar disorder) and a substance use disorder. Ten participants will attend weekly group drama therapy sessions for 12 weeks, then put on a performance.…
Phase: NA • Sponsor: Boston Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
-
Can a smartphone app bridge the gap between primary care and addiction treatment?
Knowledge-focused ENROLLING_BY_INVITATIONThis study from Mayo Clinic tests whether a smartphone app called Senyo Health can help connect people with substance use disorders to treatment through their primary care doctor. Sixty participants will use the app for 12 weeks, which includes therapy modules, weekly check-ins w…
Phase: NA • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
-
AI alert aims to curb opioid overdoses in real time
Knowledge-focused OngoingThis study tests a machine-learning tool that gives doctors a pop-up alert when they prescribe opioids to a patient at high risk of overdose. The alert explains why the patient is at risk and suggests safer options, like prescribing naloxone or referring to pain therapy. Research…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
-
Study on money and addiction recovery pulled before starting
Knowledge-focused TerminatedThis study aimed to understand how a person's socioeconomic status (like income and education) affects their recovery from substance use disorder. Researchers planned to follow adults in early recovery for up to 3 years, measuring changes in social functioning, quality of life, a…
Sponsor: Virginia Polytechnic Institute and State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
-
New app aims to support recovery for recently released inmates with dual diagnoses
Knowledge-focused OngoingThis study is developing and testing a smartphone app called R-Assist for people recently released from jail who have both substance use and mental health disorders. The app tracks symptoms, connects users to resources like housing and recovery groups, and measures how easy it is…
Phase: NA • Sponsor: Meaningful Measurement, Inc • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
-
Personal navigators may boost substance use treatment success
Knowledge-focused OngoingThis study tests whether a "Care Navigator" — a personal guide — can help people with substance use problems start and stay in treatment. About 360 adults who call a mental health access center will be randomly assigned to get usual care or extra help from a navigator. The goal i…
Phase: NA • Sponsor: Kaiser Permanente • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
-
Sound waves to the brain: a new hope for addiction?
Knowledge-focused OngoingThis early study is testing whether focused ultrasound, a non-invasive technique that uses sound waves to target specific brain areas, is safe and feasible for people with opioid or other substance use disorders. The study involves 20 adults aged 22-60 who are currently in treatm…
Phase: NA • Sponsor: Manish Ranjan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC