Fetal alcohol spectrum disorder
MONDO:0000408A group of disorders caused by a prenatal exposure to maternal consumption of alcohol leading to a range of behavioral, cognitive and neurological deficits in the offspring. It is characterized by physical growth problems, distinct facies, and varying psycho-neurological issues.
Also known as: fetal alcohol spectrum disorders, foetal alcohol spectrum disorders, FAE (fetal alcohol effects), FAEs (fetal alcohol effects), FASD, FASDs, alcohol related birth defects, alcohol related neurodevelopmental disorder
153 clinical trials for this condition and its sub-types.
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Broader categories
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New community program targets COPD and mental health together
Disease control CompletedThis completed trial in Xishui, China, tested a community-based program for 3,571 adults aged 35 and older who were at high risk for COPD and had mental health symptoms. The program included lung function tests, digital mental health support, smoking cessation help, and health ed…
Phase: NA • Sponsor: Peking Union Medical College • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Web therapy for addiction shows promise in native communities
Disease control CompletedThis study tested a web-based addiction treatment program that was culturally adapted for American Indians and Alaska Natives. 53 adults in outpatient treatment used the program for 12 weeks. The goal was to see if it helped them stay away from drugs and alcohol and to decide if …
Phase: NA • Sponsor: New York State Psychiatric Institute • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Mindfulness may keep women in addiction treatment longer
Disease control CompletedThis study tested a mindfulness program designed for women in residential treatment for substance use disorders. The program, called Mindfulness-Based Relapse Prevention for Women (MBRP-W), teaches stress management skills to help women stay in treatment and avoid relapse. Resear…
Phase: NA • Sponsor: University of Southern California • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Can a coach in the ER help people beat addiction?
Disease control CompletedThis study tested whether peer recovery coaches in emergency departments can help people with substance use disorders connect to treatment and support. 144 adults were randomly assigned to get in-person coaching, coaching via video call, or just a list of resources. Researchers f…
Phase: NA • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Can a smartphone app curb drinking during pregnancy?
Disease control CompletedThis study tested a phone-based program called MommyCheckup to see if it helps pregnant women who drink alcohol cut back or stop. The program includes a short motivational video and tailored text messages. Researchers enrolled 384 pregnant women across three states to see if the …
Phase: NA • Sponsor: Michigan State University • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Can one doctor visit tackle both addiction and depression?
Disease control CompletedThis study tested whether a team-based care model can help people with both opioid use disorder and mental health issues like depression or anxiety. 254 adults in primary care received either full collaborative care for both conditions or just mental health support. The goal was …
Phase: NA • Sponsor: University of Washington • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Smartphone app and digital pill aim to boost HIV prevention in substance users
Disease control CompletedThis study tested a digital pill and smartphone app to help people with substance use disorders take their HIV prevention medication (PrEP) consistently. Thirty HIV-negative men who have sex with men and have moderate to severe substance use disorder participated. They used a dig…
Phase: PHASE3 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 26, 2026 18:31 UTC
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Mediterranean diet shows promise for metabolic health in psychiatric patients
Disease control CompletedThis completed study tested whether a Mediterranean diet could improve metabolic syndrome markers in 30 hospitalized adults with psychiatric conditions. Participants followed either a Mediterranean diet or a standard hospital diet for 8 weeks, then switched. Researchers measured …
Phase: NA • Sponsor: King Saud University • Aim: Disease control
Last updated Jun 26, 2026 15:01 UTC
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New app aims to protect native women from alcohol-affected pregnancies
Prevention CompletedThis study is developing and testing a smartphone app designed for Native American women to help them avoid pregnancy affected by alcohol. Researchers will gather feedback and pilot test new features with 407 women who are at risk. The goal is to reduce risky drinking and improve…
Phase: NA • Sponsor: University of Virginia • Aim: Prevention
Last updated Jun 27, 2026 14:00 UTC
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Mindfulness program shows promise in preventing relapse, but tiny study limits conclusions
Prevention CompletedThis small pilot study tested an 8-week mindfulness and meditation program in 3 adults with substance use disorders. Participants reported lower stress and improved mindfulness after the program. One person stayed sober long-term, while two relapsed within a year. The study shows…
Sponsor: Bout Me Healing • Aim: Prevention
Last updated Jun 27, 2026 09:06 UTC
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Smartphone tool helps native teens prevent alcohol-related birth defects
Prevention CompletedThis study tested a culturally adapted mobile health program called Mobile CHOICES to help urban American Indian and Alaska Native young women (ages 16-20) avoid drinking alcohol during pregnancy. The goal was to reduce the risk of Fetal Alcohol Spectrum Disorders, which cause li…
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Prevention
Last updated Jun 27, 2026 07:54 UTC
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Counseling program aims to boost mental health and HIV prevention in young women
Symptom relief CompletedThis study tested a counseling program called Youth Friendship Bench SA for young women aged 18-25 in South Africa who had symptoms of depression, anxiety, or stress. The program included individual and group counseling sessions, plus optional text reminders. The goal was to see …
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jun 28, 2026 00:00 UTC
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Can a smartphone app help people stay sober? new study says maybe.
Symptom relief CompletedThis study tested whether a digital mindfulness app is practical and acceptable for people in early recovery from substance use disorders. 36 participants were randomly assigned to standard group therapy alone or standard therapy plus the app for 8 weeks. The main goal was to see…
Phase: NA • Sponsor: Yale University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New therapy shows promise for healing war wounds in rwanda
Symptom relief CompletedThis study tested a type of group therapy called Resilience-Oriented Therapy (RoT) for adults in Rwanda who were struggling with mental health issues like trauma, depression, anxiety, or anger. 427 people took part, and the therapy was tailored to each person's main problem, such…
Phase: NA • Sponsor: Alexandros Lordos, PhD • Aim: Symptom relief
Last updated Jun 27, 2026 13:01 UTC
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Video game therapy shows promise for mental health
Symptom relief CompletedThis study tested whether a 4-week program using active video games (exergames) on the Nintendo Switch could help adults with mental illness feel better and stay motivated. Twelve participants were split into two groups: one played exergames, the other continued their usual routi…
Phase: NA • Sponsor: University of Salamanca • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Personalized craving scale shows promise for addiction treatment
Symptom relief CompletedThis study tested whether adding a personalized therapy scale to standard treatment helps reduce cravings in people with substance use disorders or behavioral addictions like gambling. 151 adults seeking outpatient care participated. The approach aimed to tailor treatment to each…
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Breathwork breakthrough? SKY program may ease cravings in recovery
Symptom relief CompletedThis study tested a breathing and meditation program called SKY Recovery in 100 people recovering from substance use disorder at a residential center. Participants either took the program right away or after a delay. Researchers measured changes in emotion regulation, cravings, a…
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Can online therapy and a buddy help beat addiction?
Symptom relief CompletedThis study looked at whether an online cognitive behavioral therapy program, called Breaking Free Online, helps people with substance use disorder cut back on their drug or alcohol use. About 200 adults from an outpatient addiction program took part. Some got standard care with g…
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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New telehealth therapy targets loneliness to curb substance use in veterans
Symptom relief CompletedThis study tested a special type of talk therapy (cognitive-behavioral therapy, or CBT) delivered over telehealth to help veterans who feel lonely and struggle with substance use. The goal was to see if the program was practical and well-liked by participants. Thirty-six veterans…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Can a special therapy help teens with fetal alcohol disorders?
Symptom relief CompletedThis study tested whether a therapy called dialectical behavior therapy (DBT) is helpful and acceptable for teens aged 14–17 with fetal alcohol spectrum disorders (FASD). Nine teens and their caregivers took part in a program that included individual therapy, group skills trainin…
Phase: NA • Sponsor: University of Rochester • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Can peer support groups boost recovery in mental health?
Symptom relief CompletedThis study tested a 10-week peer support program called 'Paths to everyday life' for adults with mental health difficulties. Participants were randomly assigned to either the peer support group plus usual services, or usual services alone. The goal was to see if the program impro…
Phase: NA • Sponsor: Amager Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Night help for moms in recovery: can respite care improve sleep and Well-Being?
Symptom relief CompletedThis study tested whether providing overnight infant care and parenting support helps new mothers with substance use disorder living in residential treatment programs. 41 mothers participated, and researchers measured how many enrolled, completed the program, and gave feedback. T…
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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New app aims to ease parenting challenges for kids with FASD
Symptom relief CompletedThis study tested a smartphone app called FMF Connect for parents and caregivers of children with fetal alcohol spectrum disorders (FASD). The app provides helpful information and peer support to manage children's behavior. 129 parents participated, and researchers measured chang…
Phase: NA • Sponsor: University of Rochester • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Can Man's best friend boost mental health? new study says maybe.
Symptom relief CompletedThis study tested a 10-session dog-assisted therapy program for 60 adults with severe mental illness. The goal was to see if spending time with trained therapy dogs could help participants build positive mental health behaviors like communication and socialization. Researchers me…
Phase: NA • Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Green tea extract may sharpen minds of kids with fetal alcohol syndrome
Symptom relief CompletedThis pilot study tested whether a daily dose of EGCG, a natural compound found in green tea, could improve cognitive performance in 36 children aged 7 to 14 with fetal alcohol syndrome. The children took EGCG for one year and had their thinking skills measured at the start, at 6 …
Phase: NA • Sponsor: Fundacion Clinic per a la Recerca Biomédica • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Exercise on campus: a new hope for stressed students?
Symptom relief CompletedThis study tested a 6-week supervised physical activity program for university students dealing with mild-to-moderate mental health issues like stress, anxiety, or feeling isolated. Seventeen students took part in group exercise sessions including walking, aerobics, and strength …
Phase: NA • Sponsor: York St John University • Aim: Symptom relief
Last updated Jun 26, 2026 18:21 UTC
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New brain scans could unlock secrets of drug addiction
Knowledge-focused CompletedThis study aims to create and improve cognitive tasks used during functional MRI scans to better understand how drugs affect the brain. It involves 525 healthy volunteers, including both drug users and non-users, aged 18 to 65. Participants perform tasks like memory tests or reac…
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Can peers help others recover? small study tests new program
Knowledge-focused CompletedThis study tested whether a 10-week recovery program, co-led by a peer with mental illness and a professional, is feasible for people with mental illness in Taiwan. Twenty participants completed the program, which focused on recovery concepts, strengths, and goal setting. Researc…
Phase: NA • Sponsor: National Cheng-Kung University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Hospital study reveals who gets help for addiction in the ER
Knowledge-focused CompletedThis study looked back at the records of 652 patients who were seen in the emergency department of a French hospital and then referred to a special addiction liaison team. The goal was to understand the social and medical backgrounds of these patients. The findings could help hos…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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New web tool aims to get sick healthcare workers back on the job faster
Knowledge-focused CompletedThis study tested a web application called PRATICAdr 2.0, designed to help healthcare workers on sick leave due to common mental disorders like depression or anxiety return to work. The app helps coordinators track progress and improve communication. Researchers compared workers …
Phase: NA • Sponsor: Université du Québec a Montréal • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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AI therapists in training: can computers teach better counseling?
Knowledge-focused CompletedThis study tested whether artificial intelligence (AI) can realistically simulate conversations between a therapist and a person with a mental health problem. Researchers used 520 simulated sessions to see if the AI could follow proper therapy techniques. The goal is to use these…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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App aims to support recovery for justice-involved individuals
Knowledge-focused CompletedThis study tested whether a mobile app could help people on probation or parole who are receiving treatment for substance use disorder. 31 adults used the app alongside their usual care. Researchers measured how easy the app was to use and how satisfied participants were with it.
Phase: NA • Sponsor: Friends Research Institute, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Brain scans and thinking tests aim to unlock secrets of Self-Harm
Knowledge-focused CompletedThis study looked at how thinking skills and brain activity differ in people who self-harm compared to those who don't. Researchers interviewed 316 adults and gave them thinking tests, with some also having brain scans. The goal was to better understand self-harm to help create m…
Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Peer support after psychiatric stay shows promise in small VA study
Knowledge-focused CompletedThis study tested a program called Recovery Bridge, where trained peer specialists (people with lived experience of mental illness) helped veterans leaving a psychiatric hospital connect to outpatient care and community life. Fifteen veterans took part to see if the program was f…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Heart and mind: new study explores the hidden links between cardiovascular disease and mental illness
Knowledge-focused CompletedThis completed study looked at 400 people with both heart disease and a mental health condition (like depression or anxiety). Researchers used questionnaires, blood tests, and imaging to find shared risk factors and biological markers. The goal was to better understand how these …
Sponsor: Ningbo No. 1 Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Can training reduce stigma in healthcare? new study tests Anti-Bias program
Knowledge-focused CompletedThis study tested whether an anti-stigma training program for healthcare providers improves attitudes toward people with mental illness or substance use problems. About 485 staff and clients from six health centers took part, with three centers receiving the training and three no…
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Can smartphone apps help fight addiction in primary care? large study tests new approach.
Knowledge-focused CompletedThis study looked at the best ways to bring FDA-approved digital treatments (reSET and reSET-O) for opioid and other substance use disorders into primary care clinics. Over 18,000 adults who screened positive for substance use took part. Researchers tested whether health coaching…
Phase: NA • Sponsor: Kaiser Permanente • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Sleep struggles widespread in psychiatric wards
Knowledge-focused CompletedThis study looked at how often insomnia occurs in people hospitalized for psychiatric conditions. Researchers checked 427 patients at 11 hospitals in Switzerland and Germany. They also explored whether age, gender, or type of disorder made insomnia more likely.
Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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New study checks if depression scale works for those with addiction
Knowledge-focused CompletedThis study looked at whether a questionnaire called the Behavioral Activation for Depression Scale (BADS) is a good tool for measuring depression-related behaviors in people with substance use disorders. Researchers analyzed answers from 289 adults receiving treatment for substan…
Sponsor: Lauro Gutiérrez Castro • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Can doing meaningful activities boost recovery in mental illness? new study says maybe.
Knowledge-focused CompletedThis study tested an 8-month program called 'Meaningful Activities and Recovery' (MA&R) for people with mental illness. The program helps people take part in activities that matter to them. 139 adults took part to see if the program improves activity engagement, recovery, and qua…
Phase: NA • Sponsor: Amager Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Scientists hunt for genetic fingerprints to detect FASD earlier
Knowledge-focused CompletedThis study looked at 188 children (ages 0-18) with Fetal Alcohol Spectrum Disorders (FASD) in Reunion Island to better describe the condition and find a unique "epigenetic signature" in their DNA. Researchers collected blood and cheek swabs from a small group of children with FAS…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de la Réunion • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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AI coaching for addiction counselors? study tests new approach
Knowledge-focused CompletedThis study tested a new way to help addiction treatment clinics use an AI platform that coaches counselors in evidence-based techniques. Researchers worked with 479 leaders and staff from state agencies and clinics in Oregon and Indiana. The goal was to see if this strategy impro…
Phase: NA • Sponsor: University of California, San Diego • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Can a training program help therapy interns talk better with patients?
Knowledge-focused CompletedThis study tested a program called iCOT to improve how occupational therapy interns communicate with patients in mental health settings. The program included online training and feedback from patients, supervisors, and experts. Researchers compared interns who received iCOT to da…
Phase: NA • Sponsor: Chang Gung Memorial Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Did a simple phone call keep chronic patients out of the hospital?
Knowledge-focused CompletedThis study tested whether a systematic phone call from a medical student, supervised by a general practitioner, could reduce hospitalizations in patients with chronic heart or mental health conditions during the COVID-19 lockdown in France. Over 22,000 patients aged 70 and older …
Phase: NA • Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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New manual seeks to boost black representation in addiction trials
Knowledge-focused CompletedThis completed study worked with 65 African American/Black adults who use cocaine or other illicit substances to develop a manual called I-DREM. The goal was to gather their feedback on how to improve recruitment and retention in substance use disorder clinical trials. Participan…
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Study aims to make mental health support for kids more efficient and affordable
Knowledge-focused CompletedThis study tested different parts of a family navigation program to see which ones work best for helping low-income and minority families get mental health services for their children. 312 children aged 3-12 who showed signs of behavioral health concerns took part. The goal was t…
Phase: NA • Sponsor: Boston Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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AI could revolutionize online therapy by predicting who benefits most
Knowledge-focused CompletedThis study used artificial intelligence to predict how engaged people would be in online therapy and how much their symptoms would improve. Researchers analyzed data from over 6,600 adults who took part in a digital psychotherapy program. The goal was to create fair and accurate …
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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New app aims to boost college success for veterans with mental health struggles
Knowledge-focused CompletedThis study created and tested a mobile app called VetEd for student veterans dealing with mental health issues like depression, PTSD, or anxiety. The goal was to help them manage academics, mental health, and find resources. Researchers worked with 13 veterans to see if the app w…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Hidden ADHD: study reveals how many adults are undiagnosed
Knowledge-focused CompletedThis completed study looked at 224 adults who already had at least one psychiatric condition to see how many also had undiagnosed ADHD. Researchers measured how often ADHD was missed and tracked quality of life in those diagnosed. The goal is to highlight the need for better dete…
Sponsor: Takeda • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Can changing clinic policies and training doctors reduce stigma around addiction?
Knowledge-focused CompletedThis study tested whether combining a policy change with professional training can reduce stigma toward substance use in mental health clinics. Twelve providers from two sites participated. The goal was to see if the combined approach improves how often substance use is addressed…
Phase: NA • Sponsor: Wayne State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC