Endocardium disorder

This trial tests a new model where patients with infections receive intravenous antibiotics at home instead of staying in the hospital. Nurses from a municipal response team visit the patient, while hospital doctors oversee the treatment remotely using telemedicine and welfare te…

This study compares two approaches for replacing an infected aortic valve: using a cryopreserved aortic homograft (a preserved human donor valve) versus conventional mechanical or tissue prosthetic valves. The goal is to see which method leads to fewer complications, such as deat…

This trial investigates whether a shorter course of antibiotics, tailored to each patient's response, can treat left-sided endocarditis as safely as the standard 4-6 week regimen. Adults with endocarditis caused by specific bacteria (Streptococci, Enterococcus faecalis, or Staphy…

This trial investigates whether a shorter course of antibiotics, tailored to each patient's response, can safely treat bacterial endocarditis. Standard treatment lasts 4-6 weeks, but this study tests a personalized approach based on factors like fever and blood tests. The goal is…

This study tests whether a bedside device called Quantra can help doctors decide when to give blood transfusions during complex heart surgery. The device measures how well a patient's blood clots in real time. Researchers hope this will reduce the number of blood products (like r…

This study tests a new blood test that looks for bacterial DNA to quickly identify the germ causing infective endocarditis, a serious heart valve infection. Current methods take up to 5 days, delaying the right antibiotics. The study will enroll 200 adults with suspected endocard…

This observational study looks back at 22,000 adults in Sweden diagnosed with infective endocarditis, a serious heart valve infection, since 1997. By linking national health records, researchers aim to understand which patients benefit most from valve surgery and what factors aff…

This study was designed to look at how the immune system might contribute to heart valve damage in people with infective endocarditis, a serious bacterial infection of the heart. Researchers planned to analyze blood and heart valve tissue from patients to see if immune cells mist…

This study looks at how infective endocarditis, a serious heart infection, has changed in Taiwan between 2006 and 2022. Researchers will analyze data from over 2,200 patients to spot trends in who gets the disease and how it progresses. The goal is to use this information to impr…