Cystitis

This early-phase trial tests whether a robotic bladder transplant from a deceased donor is feasible and safe for people with severe bladder problems. Only 5 participants will be enrolled. The main goal is to see if the transplanted bladder gets good blood flow. If it works, it mi…

This study looked at whether adding the drug cidofovir to usual care helps people who develop painful bladder bleeding from the BK virus after a stem cell transplant. About 27 participants received either cidofovir or standard supportive care. The goal was to see if symptoms impr…

This study looks at how well a new robotic surgery system (Medtronic Hugo) works for urologic procedures like removing prostate, bladder, or kidney tumors. About 144 adults will have surgery with the robot, and doctors will check if the surgery is completed without switching to a…

This Phase 3 trial tests whether Raphamin, an oral tablet, can prevent repeat episodes of chronic bacterial cystitis (a type of urinary tract infection) in women. About 415 women with frequent infections will take either Raphamin or a placebo for six months. The main goal is to s…

This study tests whether adding pulsed electromagnetic field (PEMF) therapy to standard bladder instillations of heparin and bupivacaine can better reduce chronic pelvic pain in women with interstitial cystitis/bladder pain syndrome. Twenty female adults who already receive bladd…

This study looks at two treatments for women with painful bladder syndrome: bladder instillations (medication put directly into the bladder) and pelvic floor physical therapy (exercises to relax tight muscles). The goal is to see which works better to reduce pain and urinary symp…

This study tests whether a non-invasive magnetic brain stimulation technique, called rTMS, can reduce pain in women with interstitial cystitis or bladder pain syndrome. The treatment targets brain areas that control pelvic floor muscles, aiming to lower pain by improving how the …

This study tests a two-phase plant-based treatment for women who get frequent bladder infections (at least 4 per year). The treatment uses antibacterial essential oils during an infection and medicinal plants long-term to prevent future episodes. The goal is to see if this approa…

This study planned to see if a 6-week supervised exercise program could reduce symptoms of interstitial cystitis (painful bladder syndrome) and improve quality of life in adult women. Participants would have walked and done light strength training three times a week. However, the…

This study from the Cleveland Clinic is looking at whether certain migraine medications (CGRP inhibitors) can also improve bladder symptoms like urgency, frequency, and pain. About 200 women with hard-to-treat migraines and bladder issues will be followed for 3 months. Their symp…