World's first robotic bladder transplant attempted in tiny trial

NCT ID NCT05462561

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests whether a robotic bladder transplant from a deceased donor is feasible and safe for people with severe bladder problems. Only 5 participants will be enrolled. The main goal is to see if the transplanted bladder gets good blood flow. If it works, it might offer an alternative to current treatments, but lifelong immune-suppressing drugs are required.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Robotic vascularized composite bladder allograft transplantation
What this could lead to
If successful, this could offer a new surgical option for people with severe bladder problems who currently need bowel-based urinary diversion.
What could go wrong
This is a very early, first-in-human trial with only 5 participants. The procedure is complex, carries risks of rejection and complications, and requires lifelong immunosuppression.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • USC / Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.