World's first robotic bladder transplant attempted in tiny trial

NCT ID NCT05462561

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests whether a robotic bladder transplant from a deceased donor is feasible and safe for people with severe bladder problems. Only 5 participants will be enrolled. The main goal is to see if the transplanted bladder gets good blood flow. If it works, it might offer an alternative to current treatments, but lifelong immune-suppressing drugs are required.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Robotic vascularized composite bladder allograft transplantation

What this could lead to

If successful, this could offer a new surgical option for people with severe bladder problems who currently need bowel-based urinary diversion.

What could go wrong

This is a very early, first-in-human trial with only 5 participants. The procedure is complex, carries risks of rejection and complications, and requires lifelong immunosuppression.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

infiltrating bladder urothelial carcinoma urinary bladder disorder Urinary Bladder, Neurogenic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • USC / Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States