Coronavinae infectious disease

This early-stage trial tests a new booster vaccine called Boost-2867 in 140 healthy adults who have already been vaccinated against COVID-19. The vaccine is given either as a shot with or without adjuvants (ingredients that boost immune response) or as a nasal spray without adjuv…

This study tests two updated mRNA COVID-19 vaccines (mRNA-1283 and mRNA-1273 variant formulation) in 30,000 healthy adults aged 50 to 64 who are not at high risk for severe COVID-19. The goal is to see if these vaccines prevent symptomatic COVID-19 compared to a placebo. Research…

This large study is testing updated mRNA vaccines designed to protect against newer Omicron variants of COVID-19 in healthy children aged 6 months to 12 years. Over 4,000 participants will receive one or more doses depending on their age and vaccination history. Researchers are m…

This Phase 3 trial tests an updated COVID-19 vaccine (BNT162b2, 2025/2026 formulation) in 343 children aged 5 to 11 who have medical conditions that put them at high risk for severe COVID-19. All participants receive one dose and are monitored for about 6 months to check safety a…

This study was designed to test whether the drug itolizumab could help hospitalized COVID-19 patients recover faster. The trial was planned for 18 years and older with confirmed COVID-19 pneumonia and low oxygen levels. However, the study was withdrawn before enrolling any partic…

This study looks at whether a special team of doctors and nurses can treat adults with suspected infections at home, instead of sending them to the hospital. About 500 people will be randomly assigned to either standard hospital care or home-based care from a mobile response team…

This study aimed to see if the drug sarilumab could help hospitalized COVID-19 patients with severe breathing distress. It planned to compare one or two doses of sarilumab against a placebo. However, the study was withdrawn before enrolling any participants, so no results are ava…

This study tests two new devices (imPulse Una and TOR) that use sound waves to detect COVID-19, flu, and RSV without needles or swabs. About 300 adults with or without symptoms will have a quick, painless scan. The goal is to see if these e-stethoscopes can accurately identify th…

This study aimed to see if the BCG vaccine, originally for tuberculosis, could reduce the severity of COVID-19 in healthcare workers in Medellín, Colombia. It planned to give a single dose of BCG or a placebo to 0 participants (doctors, nurses, and nursing assistants) who were di…

This early-stage study is testing a new tablet version of the COVID-19 drug ibuzatrelvir in 18 healthy adults. Researchers want to see how much of the drug gets into the blood when taken as a whole tablet, dispersed in water, or with food. The goal is to compare the new tablet to…

This study looks at how the immune system of patients in the intensive care unit (ICU) responds to severe infections caused by viruses or bacteria. Researchers will take extra blood samples from 38 adults to analyze immature granulocytes, a type of immune cell. The goal is to see…

This study follows 583 adults who recovered from COVID-19 or were close contacts. Researchers will track their health, mental well-being, and immune responses over 3 years to understand long-term effects and whether prior infection prevents reinfection. Participants undergo regul…

This study planned to test telemonitoring for older adults (75+) in nursing homes with confirmed or probable COVID-19. The goal was to see if remote monitoring could improve healthcare management and reduce deaths within 30 days. However, the study was withdrawn before enrolling …

This study collects blood samples and medical information from 201 adults diagnosed with COVID-19. The goal is to create a resource that researchers can use to study the virus and improve understanding of the disease. Participants provide samples and allow their health data to be…

This study is creating a biobank of blood samples and health data from 100 people who have recovered from COVID-19. Researchers will use this information to better understand recovery and long-term effects. No new treatments are being tested; the goal is to provide resources for …

This study tracks over 4,200 people in South Korea who received a SPIKEVAX COVID-19 vaccine to see if any side effects occur over time. Participants are aged 12 or older depending on the vaccine version. The goal is to gather real-world safety data, not to test if the vaccine wor…

This study aimed to see if a computer could learn to predict how long a patient would stay in a home hospital program. Researchers planned to use data from past patients to train the computer. However, the study was withdrawn before any patients were enrolled, so no results are a…

This study follows 500 ICU patients to compare long-term mental and physical health between those with and without COVID-19. Researchers use surveys and tests to measure quality of life, thinking skills, and emotional well-being. The goal is to identify specific problems caused b…

This study tests whether temperature sensors placed inside a Venturi mask can monitor breathing patterns in 82 patients hospitalized with pneumonia and respiratory failure. The goal is to see if these patterns can detect early signs of deterioration before patients need a breathi…

This study looks at immune cells from people with autoimmune diseases (like lupus), people with infections, and healthy volunteers. Researchers want to understand how these cells differ and what makes them attack the body in autoimmune conditions. The study involves blood and bon…