New nasal spray COVID booster enters human testing

NCT ID NCT07221162

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 25 times

Summary

This early-stage trial tests a new booster vaccine called Boost-2867 in 140 healthy adults who have already been vaccinated against COVID-19. The vaccine is given either as a shot in the arm or as a nasal spray, with some shot versions including an adjuvant to boost the immune response. The main goal is to check safety and how well the body's immune system responds.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Center for Immunization Research, Johns Hopkins Bloomberg School Public Health

    RECRUITING

    Baltimore, Maryland, 21205, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke Vaccine and Trials Unit

    RECRUITING

    Durham, North Carolina, 27703, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kaiser Permanente Washington Health Research Institute

    RECRUITING

    Seattle, Washington, 98101-1466, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Saint Louis University Center for Vaccine Development

    RECRUITING

    St Louis, Missouri, 63104-1015, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California San Francisco - Zuckerberg San Francisco General Hospital - Division of Human Immunodeficiency Virus, Infectious Disease, and Global Medicine

    RECRUITING

    San Francisco, California, 94110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Pittsburgh - Medicine - Infectious Diseases

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Rochester Medical Center - Vaccine Research Unit

    RECRUITING

    Rochester, New York, 14642-0001, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.