Conversion disorder
MONDO:0002104Conversion disorder is a disorder in which a person experiences blindness, paralysis, or other symptoms affecting the nervous system that cannot be explained solely by a physical illness or injury. Symptoms usually begin suddenly after a period of emotional or physical distress or psychological conflict. Conversion disorder is thought to be caused by the bodys reaction to a stressful physical or emotional event. Some research has identified potential neurological changes that may be related to symptoms of the disorder. Diagnosis of conversion disorder is based on identifying particular signs that are common among people with the disorder, as well as performing tests to rule out other causes of the symptoms. Treatment may include psychotherapy, hypnosis, and stress management training to help reduce symptoms. Treatment of any underlying psychological disorder is also recommended. The affected body part may require physical or occupational therapy until symptoms resolve.
Also known as: conversion hysterical neurosis, FND, functional movement disorder, functional neurological disorder
48 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
Liver cancer remission: is surgery still needed?
Disease control CompletedThis study looked at liver cancer patients whose tumors shrank completely after non-surgical treatments like chemoembolization and immunotherapy. Researchers compared those who then had surgery to remove any remaining tissue versus those who simply watched and waited. The goal wa…
Phase: PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
-
Can an online program ease the distress of unexplained physical symptoms?
Symptom relief CompletedThis study tested whether an internet-based exposure therapy program can reduce distress related to physical symptoms better than standard education about healthy lifestyle habits. 161 adults in Stockholm with significant distress from somatic symptoms participated. The treatment…
Phase: NA • Sponsor: Region Stockholm • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
-
Shocking therapy may help kids with CP move better
Symptom relief CompletedThis study tested whether task-specific electrical stimulation can improve upper limb motor skills in 30 children aged 4 to 7 with spastic quadriplegia cerebral palsy. The therapy uses mild electrical pulses to activate muscles during functional tasks. The goal was to see if this…
Phase: NA • Sponsor: Kafrelsheikh University • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
-
Brain stimulation shows promise for unexplained paralysis
Symptom relief CompletedThis study tested whether a non-invasive brain stimulation technique called rTMS could help people with psychogenic paralysis (paralysis with no physical cause). 66 participants received two sessions of either real or sham rTMS over two days. The main goal was to see if paralysis…
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Symptom relief
Last updated Jun 27, 2026 12:10 UTC
-
Could magnetic pulses ease mysterious movement problems?
Symptom relief CompletedThis pilot study tested whether transcranial magnetic stimulation (TMS), a non-invasive brain stimulation technique, can improve motor symptoms in people with functional neurological disorder (FND). Fifty-one adults with limb weakness received TMS over the motor cortex. The study…
Phase: NA • Sponsor: King's College London • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
-
Talk therapy over video may ease Stress-Related seizures
Symptom relief CompletedThis pilot study tested whether prolonged exposure teletherapy can help adults with psychogenic nonepileptic seizures (PNES) and PTSD. Forty-four participants received either the teletherapy or standard education about PNES. The goal was to see if the therapy reduces seizure freq…
Phase: NA • Sponsor: Northeast Regional Epilepsy Group • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
-
App-Based CBT shows promise for functional tremor
Symptom relief CompletedThis study tested a 4-week app-based cognitive behavioral therapy (CBT) program in 20 people with functional tremor. Participants used the app to practice reframing upsetting thoughts and were compared to a group that simply reflected on their day. The goal was to see if the CBT …
Phase: NA • Sponsor: Medical University of Graz • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
-
Could EMDR therapy help calm the Brain's faulty signals?
Symptom relief CompletedThis study tested whether a therapy called EMDR (eye movement desensitisation and reprocessing) could help people with functional neurological disorder (FND), a condition where the brain doesn't send signals properly, causing symptoms like seizures, shaking, or weakness. Fifty ad…
Phase: NA • Sponsor: South West London and St George's Mental Health NHS Trust • Aim: Symptom relief
Last updated Jun 26, 2026 18:33 UTC
-
Group therapy shows promise for teens battling anxiety and depression
Symptom relief CompletedThis study tested a group version of a therapy program called the Unified Protocol for teens with emotional disorders like anxiety and depression. Thirty-one adolescents took part in 16 weekly group sessions at a public mental health center in Spain, along with three parent sessi…
Phase: NA • Sponsor: Universidad Nacional de Educación a Distancia • Aim: Symptom relief
Last updated Jun 26, 2026 17:39 UTC
-
Magic mushroom compound probes brain in FND patients
Knowledge-focused CompletedThis study looks at how a single dose of psilocybin, the active ingredient in magic mushrooms, affects brain networks in 24 adults with functional neurological disorder (FND). Participants receive the drug with therapeutic support, and brain scans are taken before and after to se…
Phase: NA • Sponsor: King's College London • Aim: Knowledge-focused
Last updated Jul 25, 2026 00:00 UTC
-
What sets pro soccer players apart? study measures key physical differences
Knowledge-focused CompletedThis observational study compares functional movement, dynamic balance, and lower body strength between 144 professional and amateur male soccer players. Participants undergo standardized tests like the Functional Movement Screen, Y-Balance Test, and jump and strength assessments…
Sponsor: Istanbul Gelisim University • Aim: Knowledge-focused
Last updated Jul 16, 2026 00:00 UTC
-
New study reveals three types of PNES seizures
Knowledge-focused CompletedThis completed study looked at video-EEG recordings from 50 adults with psychogenic nonepileptic seizures (PNES). Researchers aimed to identify distinct patterns in how these seizures look and behave. They classified events into three clusters based on features like movement and …
Sponsor: Tepecik Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
-
Brain wave study sheds light on PNES seizures
Knowledge-focused CompletedThis completed study looked back at the records of 50 adults diagnosed with psychogenic nonepileptic seizures (PNES) who had video-EEG monitoring. Researchers reviewed the video and brain wave data to describe the different types of seizure movements and other features. The goal …
Sponsor: Saglik Bilimleri Universitesi • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
-
Brain scans may predict recovery in conversion disorder
Knowledge-focused CompletedThis study looked at 20 people with a first episode of motor conversion disorder, a condition where psychological stress causes physical symptoms like paralysis. Researchers used PET scans to measure brain metabolism at the start of symptoms and checked if those patterns related …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
-
Scientists hunt for biological clues in mysterious movement disorder
Knowledge-focused CompletedThis study examined 20 adults experiencing their first episode of conversion disorder (a condition where psychological stress causes physical symptoms like paralysis or abnormal movements). Researchers measured inflammation markers in the blood and compared them with brain scans …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC