Can an online program ease the distress of unexplained physical symptoms?

NCT ID NCT04942028

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether an internet-based exposure therapy program can reduce distress related to physical symptoms better than standard education about healthy lifestyle habits. 161 adults in Stockholm with significant distress from somatic symptoms participated. The treatment involves gradually facing situations that trigger symptom-related distress, delivered online.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

internet-delivered exposure-based behavioral therapy

What this could lead to

If it works, this could provide an accessible online treatment option for people distressed by chronic physical symptoms, reducing healthcare costs.

What could go wrong

This is a single completed trial with 161 participants, so results may not apply broadly. The treatment requires active engagement and may not help everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Medically Unexplained Symptoms physiological malfunction arising from mental factor somatoform disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Liljeholmen University Primary Health Care Centre

    Stockholm, 11763, Sweden