Can facing symptoms Head-On boost therapy for chronic physical distress?
NCT ID NCT07757854
First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time
Summary
This trial asks whether adding structured exposure exercises to response prevention—a core part of exposure therapy—makes a meaningful difference for people who are highly bothered by persistent physical symptoms. About 360 adults with high symptom burden will be randomly assigned to receive either response prevention alone or response prevention plus exposure exercises. The study tracks changes in symptom reactivity week by week to see if the extra exposure component improves outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Behavioral therapy: exposure exercises and response prevention
- What this could lead to
- If successful, this could refine exposure-based treatments for people with persistent physical symptoms, making therapy more effective and targeted.
- What could go wrong
- The trial is early-stage and the benefit of adding exposure exercises is uncertain. Results may not apply to all patients, and therapy requires active participation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Liljeholmen University Primary Health Care Centre
Stockholm, 117 63, Sweden
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