Conversion disorder
MONDO:0002104Conversion disorder is a disorder in which a person experiences blindness, paralysis, or other symptoms affecting the nervous system that cannot be explained solely by a physical illness or injury. Symptoms usually begin suddenly after a period of emotional or physical distress or psychological conflict. Conversion disorder is thought to be caused by the bodys reaction to a stressful physical or emotional event. Some research has identified potential neurological changes that may be related to symptoms of the disorder. Diagnosis of conversion disorder is based on identifying particular signs that are common among people with the disorder, as well as performing tests to rule out other causes of the symptoms. Treatment may include psychotherapy, hypnosis, and stress management training to help reduce symptoms. Treatment of any underlying psychological disorder is also recommended. The affected body part may require physical or occupational therapy until symptoms resolve.
Also known as: conversion hysterical neurosis, FND, functional movement disorder, functional neurological disorder
48 clinical trials for this condition and its sub-types.
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A clap of thunder: could a hand clap diagnose seizures?
Diagnosis OngoingThis trial tests whether a sudden, loud hand clap can help doctors quickly tell apart epileptic seizures from psychogenic non-epileptic seizures (PNES), which look similar but have different causes. About 400 people undergoing video-EEG monitoring will receive the clap test durin…
Sponsor: Xijing Hospital • Aim: Diagnosis
Last updated Aug 05, 2026 00:00 UTC
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Training the heart to calm the brain: a new hope for functional neurological disorders?
Symptom relief OngoingThis trial tests whether heart rate variability biofeedback—a non-invasive technique that teaches people to control their heart rhythm—can ease symptoms of functional neurological disorders (FND), a condition where the brain and nervous system don't function properly despite no s…
Phase: NA • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Symptom relief
Last updated Aug 16, 2026 00:00 UTC
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Can magnetic pulses rewire the brain to ease movement symptoms?
Symptom relief OngoingThis trial tests whether a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) can improve symptoms of functional movement disorder (FMD), a condition causing involuntary movements without a known neurological cause. Adults aged 18 to 80 with a…
Phase: NA • Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Symptom relief
Last updated Aug 14, 2026 00:00 UTC
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Dance moves tested as therapy for Brain-Body disorder
Symptom relief OngoingThis study tests whether a structured dance and movement program is practical and acceptable for people with functional neurological disorder (FND), a condition where the brain doesn't send proper signals to the body. Thirty adults with FND will be randomly assigned to either dan…
Phase: NA • Sponsor: King's College London • Aim: Symptom relief
Last updated Jun 28, 2026 00:00 UTC
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Can a phone app retrain your tremor?
Symptom relief OngoingThis study tests a smartphone app called Tremor Retrainer for people with functional tremor, a movement disorder not caused by other diseases. About 20 participants aged 10 and older will use the app and be monitored via video. The goal is to see if the app is easy to use and if …
Phase: NA • Sponsor: University of Virginia • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Promising tremor device study pulled before it began
Symptom relief TerminatedThis study was designed to see if a biofeedback device called JOGO could help people with functional tremor, a condition where the body shakes uncontrollably. JOGO uses stickers on the skin to read muscle activity and then guides users through training sessions to reduce shaking.…
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Stroke mimics: new study follows patients without stroke to uncover hidden patterns
Knowledge-focused OngoingThis study looks at 20 adults who were admitted to a stroke unit with stroke-like symptoms but were found not to have a stroke or other neurological disease. The goal is to describe their thinking and behavior patterns and track their symptoms over 6 months. This research aims to…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Can we predict psychosis? global study seeks answers
Knowledge-focused OngoingThis observational study is collecting data from 2,617 young people (ages 12-30) at clinical high risk for psychosis, plus healthy controls, across 13 countries. Researchers will use clinical assessments, cognitive tests, and biomarkers to build algorithms that predict who will r…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC