Congenital diaphragmatic hernia

This study investigates whether high- or low-intensity inspiratory muscle training (IMT) better improves diaphragm function in patients who have been on mechanical ventilation for over 21 days. Using ultrasound, researchers will measure changes in diaphragm movement and thickness…

This pilot study tested a procedure called FETO, where a tiny balloon is placed in the windpipe of an unborn baby with severe congenital diaphragmatic hernia (CDH). The goal was to see if the balloon could be safely placed and removed to help the lungs grow. Four pregnant women p…

This study tested a new device (Smart-TO) that places a small balloon in the windpipe of unborn babies with congenital diaphragmatic hernia, a condition where the diaphragm has a hole and the lungs don't grow properly. The balloon is later removed using a special MRI technique. T…

This study tested a procedure called FETO (fetal endotracheal occlusion) in 20 pregnant women whose babies had a severe form of congenital diaphragmatic hernia (CDH). In CDH, a hole in the diaphragm allows abdominal organs to move into the chest, preventing the lungs from growing…

This study looked at whether a medicine called milrinone can improve oxygen levels in newborns with congenital diaphragmatic hernia (CDH), a birth defect that causes severe breathing problems. The trial included 66 babies who were on breathing machines. The goal was to see if mil…

This study tested two ways to manage pain in 70 children undergoing chest surgery. One method, the erector spinae plane block, was compared to the standard epidural block. The goal was to see which provides better pain relief and keeps the heart rate and blood pressure more stabl…

This study looked at the quality of daily life in children aged 5 to 18 who were born with a congenital diaphragmatic hernia (a hole in the diaphragm). Researchers asked the children, their parents, and siblings to fill out a questionnaire about physical and emotional well-being,…

This study looked at 21 pregnant women and their babies to understand how surgery before birth changes the immune system. The goal was to find out if immune system activation might cause early labor. Researchers collected blood samples and studied the placenta to track immune cha…

This study looked at the DNA of 73 children with a rare birth defect called isolated congenital diaphragmatic hernia (CDH), where a hole in the diaphragm allows organs to move into the chest. Researchers wanted to find new genetic changes that might cause the condition. They used…

This pilot study looked at 8 newborns with congenital diaphragmatic hernia (a hole in the diaphragm) after surgery. Researchers compared two types of breathing machines: standard ventilation and a newer method called NAVA, which senses the baby's own breathing signals to provide …