Canker sore

This study compares a new probiotic gel to a standard steroid gel for treating minor recurrent canker sores—painful mouth ulcers that make eating and talking difficult. Adults with these sores will apply either the probiotic or steroid gel four times daily for up to two weeks. Re…

This study tested whether a probiotic called Lactobacillus rhamnosus Lcr35® can reduce the number of painful canker sores in people who get them often. Twenty adults with frequent outbreaks took either the probiotic or a placebo daily for 3 months, then were monitored for another…

This study tests whether a paste made from chitosan nanoparticles can heal minor mouth ulcers and reduce pain better than a standard steroid ointment. Thirty people with recurrent aphthous stomatitis (canker sores) will apply either the chitosan paste or the steroid paste to thei…

This study compares three treatments for recurrent aphthous stomatitis (canker sores): St. John's wort oil, a topical corticosteroid, and hyaluronic acid gel. Researchers measure how well each reduces pain, shrinks ulcer size, and speeds healing in adults with a history of these …

This study tested whether a mouth rinse made from sumac, a common spice, can help heal painful canker sores and reduce pain. Thirty-eight healthy adults with minor mouth ulcers used the rinse and were monitored for healing and pain levels. Researchers also measured inflammation m…

This study tested if zinc oxide ointment can help heal painful canker sores. One hundred people with canker sores used either the zinc ointment or a placebo three times a day for six days. Researchers measured pain and how the sores affected daily life to see if the ointment made…

This study tested whether vitamin B12 tablets can ease painful mouth ulcers caused by braces, comparing them to a standard steroid gel (Kenalog). 82 adults with traumatic ulcers were split into two groups. Researchers measured pain and ulcer size after 4 and 8 days to see which t…

This pilot study tested a new treatment called non-thermal plasma (NTP) for painful mouth ulcers in 50 adults. The goal was to see if NTP could speed up healing and reduce pain better than standard laser therapy or a placebo. Participants were randomly assigned to one of three gr…