Shrimp-Derived nanoparticles could offer natural relief for painful mouth ulcers
NCT ID NCT07702474
First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time
Summary
This study tests whether a paste made from chitosan nanoparticles can heal minor mouth ulcers and reduce pain better than a standard steroid ointment. Thirty people with recurrent aphthous stomatitis (canker sores) will apply either the chitosan paste or the steroid paste to their ulcers. Researchers will measure changes in ulcer size and pain scores over time.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a paste made from chitosan nanoparticles
- What this could lead to
- If it works, this could offer a natural alternative to steroid treatments for painful mouth ulcers.
- What could go wrong
- This is a small, early-phase trial, so results may not apply broadly. The paste may not heal ulcers faster or reduce pain better than the standard treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
30 people
The number who actually took part.
- Started
-
Apr 2009
- Finished
-
Dec 2009
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients complaining of oral recurrent ulcers with signs of minor recurrent aphthous stomatitis. * History of oral recurrent ulcers with a recurrence rate of 2 to 3 times per year. * Ulcer diameter less than 1 cm at baseline. * Maximum of 4 days passed since the emergence of the current ulcer. * No use of any prior medications or treatment for the current ulcer. * Signed written informed consent. Exclusion Criteria: * Background of systemic diseases, including diabetes mellitus. * Connective tissue diseases such as Lupus. * Syndromes or diseases related to aphthous ulcers, such as cyclic neutropenia and Behcet's disease.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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