Can a vitamin soothe braces sores? new study pits B12 against standard gel

NCT ID NCT07004465

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether vitamin B12 tablets can ease painful mouth ulcers caused by braces, comparing them to a standard steroid gel (Kenalog). 82 adults with traumatic ulcers were split into two groups. Researchers measured pain and ulcer size after 4 and 8 days to see which treatment worked better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
vitamin B12 (cyanocobalamin) and triamcinolone acetonide (Kenalog)
What this could lead to
If vitamin B12 works as well as Kenalog, it could offer a simpler, over-the-counter option for managing mouth sores from braces.
What could go wrong
This is a small, completed trial with only 82 participants. Results may not apply to everyone, and vitamin B12 might not reduce pain as effectively as the standard treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

canker sore Oral Ulcer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Karbala university

    Karbala, Karbala Governorate, 56001, Iraq

  • Kerbala University

    Karbala, Kerbala, 56001, Iraq

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