Anorexia nervosa

This trial tests whether donepezil, a medication used for memory, can help adults with anorexia nervosa weaken the strong habits that drive restrictive eating. Ten participants will receive the drug for up to 8 weeks while staying in an inpatient unit, with weekly check-ins to mo…

This pilot study tests whether fecal microbiota transplant (FMT) – taking capsules made from healthy donor stool – is a feasible and acceptable treatment for 20 teens (ages 12-17) with anorexia nervosa. Participants will take FMT or placebo capsules twice a day, twice a week for …

This pilot study tests whether adding a single dose of fecal microbiota transplant (FMT) to standard psychotherapy can help people with anorexia nervosa. Thirty-six adults starting outpatient therapy will be randomly assigned to receive either therapy alone or therapy plus FMT (v…

This study explores whether a 6-week creative writing program can help 10 teens and young adults (ages 16-25) with anorexia nervosa express themselves, reflect on their experiences, and build resilience. Participants will attend weekly workshops involving reading, writing, and gr…

This trial tests FlexED, a digital game-like intervention for young women aged 15–25 with eating disorders. Over seven 20-minute sessions on a mobile phone, users follow an avatar through a story and complete interactive exercises based on Acceptance and Commitment Therapy (ACT).…

This study tests a digital program called FlexED that uses games and exercises to help young women and girls (ages 15-25) who struggle with body image and eating disorder symptoms. Participants are randomly assigned to either the FlexED program or online education modules. The go…

This study tests a slow-release melatonin (PedPRM) in 120 children aged 6 to 18 who have anorexia nervosa and trouble sleeping. Participants take either melatonin or a placebo for 13 weeks. The goal is to see if it safely improves total sleep time and related symptoms like anxiet…

This Phase 2 trial tests whether a drug called nanocrystalline megestrol acetate can help people with advanced liver cancer who are losing weight and appetite. About 88 patients will receive either the drug or a placebo for 12 weeks while also getting standard cancer therapy. The…

This study tests a short, one-time online program that uses social support to help adults with disordered eating (excluding anorexia). The goal is to see if it can reduce harmful eating symptoms and improve habits. About 111 people from rural U.S. areas will take part by filling …

This early study tests whether a non-invasive brain stimulation technique called rTMS can help reduce symptoms of anorexia nervosa in 45 people aged 14 to 24. Participants will receive 20 daily sessions of rTMS, which uses magnets to stimulate the brain. Researchers will track ch…

This study tests whether a short virtual reality (VR) program is safe and acceptable for adults with anorexia nervosa. Participants will use VR for about 20-30 minutes each weekday for one week, while continuing their usual care. The goal is to see if people are willing to try it…

This study tests a four-week psychoeducation program for parents of adolescents with anorexia nervosa. The program aims to help parents understand the disorder and support healthy eating. Seventy families will be randomly assigned to receive the program immediately or after a one…

This study tests whether a peppermint oil mouthwash can help reduce nausea, vomiting, and loss of appetite caused by chemotherapy in people with blood cancers. 72 patients will be split into two groups: one gets standard oral care, the other rinses with peppermint oil three times…

This study tests whether 3D infrared body scanning can better assess malnutrition in adolescents and young adults hospitalized with anorexia nervosa. Researchers will measure body composition and track how organ and tissue stores relate to medical stability, nutritional needs, an…

This study investigates whether a brief training task can change how people with anorexia nervosa value food. Participants view food images and focus on attributes like tastiness or healthiness, then make food choices. The goal is to see if this training makes their choices more …

This study looks at factors like treatment expectations, sense of autonomy, and patient participation in 100 people with difficult-to-treat anorexia nervosa receiving inpatient care. Researchers will also examine caregivers' attitudes toward autonomy. The goal is to gather knowle…

This study follows 307 adolescents and young adults (ages 12-22) with eating disorders who receive care at a specialized day hospital. Researchers will track changes in body mass index, eating disorder symptoms, and overall well-being over time. The goal is to understand how well…

This study follows 25 adolescent girls with anorexia nervosa over 12 months of psychiatric treatment. Researchers will measure sleep patterns, inflammation, hormones, and quality of life at the start and after one year. The goal is to see how these factors change with treatment a…

This pilot study tests a self-guided digital program called SOAR that shares science-backed sleep tips with people starting treatment for an eating disorder. The program includes videos on sleep hygiene and setting a regular sleep schedule. Researchers want to see if the program …

This study tests a structured program called TransitionED designed to help youth aged 16+ with eating disorders move from pediatric to adult healthcare. The program includes planning packages, guided meetings, and a personal profile to share with new providers. Researchers will c…

This study tests whether a brief education session about cannabis risks can increase knowledge and motivation to reduce use among people with eating disorders. 80 patients will receive either cannabis education or sleep hygiene education during their first week of a 20-week eatin…

This study looks at how the brains of women with anorexia nervosa respond to fatty food smells and images. Researchers will use brain scans to compare their reactions to those of healthy women. The goal is to understand why fatty foods cause aversion, which could help improve fut…

This study looks at sleep, daytime activity, and body rhythms in 75 adults with anorexia, bulimia, or binge-eating disorder. Participants wear a small device called an actigraph to track movement and sleep for 24 hours. Researchers will also check hormone levels and ask about moo…

This study will check how common joint hypermobility (being double-jointed) and pain are in 100 female patients aged 13-25 with anorexia nervosa. Researchers want to see if hypermobility might be a hidden cause of pain and whether jaw joint problems make eating harder. Participan…