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116076 trials found · Page 5731 of 5804
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Pfizer compares two pill forms of new drug in small Healthy-Volunteer study
Knowledge-focused CompletedThe primary purpose of this study is to measure and compare the amount of study drug in your blood after a single dose of two formulations of study drug.
Phase: PHASE1 • Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Breathing muscle training may boost tongue power, small study hints
Knowledge-focused Recruiting nowThis study aims to investigate the effects of respiratory muscle training on tongue muscle function in healthy subjects. We hypothesize that respiratory muscle training can improve strength and endurance of the tongue muscles.
Phase: NA • Sponsor: Université Catholique de Louvain • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Healthy volunteers help Fine-Tune new drug formulation
Knowledge-focused CompletedPart 1 aims to investigate the relative bioavailability of a new formulation and to assess potential food effects following oral administration of SYT-510. Part 1 will then guide dosing in Part 2, a multiple dose study which aims to assess safety, tolerability and pharmacokinetic…
Phase: PHASE1 • Sponsor: Synendos Therapeutics AG • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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New antibiotic combo tested in healthy volunteers
Knowledge-focused CompletedThis is a Phase 1, open-label, single-center PK study in healthy adult male and female participants between 18 and 55 years of age (both inclusive). Thirty-one participants will each undergo one standard bronchoscopy with bronchoalveolar lavage (BAL) following the fifth dose of c…
Phase: PHASE1 • Sponsor: Basilea Pharmaceutica • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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When you eat matters: study reveals meal Timing's impact on metabolism
Knowledge-focused CompletedThe overarching aim of this research is to study the effects of caloric content and timing of meals on measures of postprandial metabolism and cardiovascular response 1. Determine the effect of caloric content on measures of postprandial metabolic flexibility and pulse wave anal…
Phase: NA • Sponsor: George Washington University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Withings study to test smart device blood pressure prediction
Knowledge-focused TerminatedThe primary objective is to evaluate the accuracy to predict uncontrolled hypertension with Withings device data.
Sponsor: Withings • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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New drug CDX-622 tested for safety in healthy people
Knowledge-focused CompletedThis is a study to determine the safety of CDX-622 in healthy participants.
Phase: PHASE1 • Sponsor: Celldex Therapeutics • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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High heels and bunions: new study measures the link
Knowledge-focused CompletedQ angle was measured in association with wearing high heels in working women in offices located in Lahore. The measurement tool was Manchester scale and goniometer with a sample size of 80 people.
Sponsor: Superior University • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:07 UTC
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New drug TAK-004 tested in healthy people for first time
Knowledge-focused CompletedThis study is the first study with TAK-004 conducted in human beings. Participants will receive either TAK-004 or placebo. The main aim of this study is to learn how safe TAK-004 is in healthy adults and how well participants tolerate one or more doses of TAK-004. Other aims are …
Phase: PHASE1 • Sponsor: Takeda • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Rare disease study pulled before starting: scientists sought clues in cell stress
Knowledge-focused TerminatedMutations in the genes encoding cytosolic aminoacyl-tRNA synthetases are responsible for early-onset multisystemic diseases including to varying degrees interstitial lung disease, liver damage, neurological and digestive disorders, and systemic inflammation. These are rare and se…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Heart scans aim to uncover hidden damage in duchenne patients
Knowledge-focused TerminatedThe purpose of this study is to describe the progression of tissular and functional myocardial abnormalities in patients with Duchenne muscular dystrophy using cardiac magnetic resonance imaging and blood biomarkers assays.
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Heart risk study for leg artery patients pulled before start
Knowledge-focused TerminatedPeripheral artery disease, lack or blood flow to the legs, has a high prevalence in the Veteran population. In patients with severe peripheral artery disease that requires an endovascular or surgical intervention for lower leg revascularization, the long-term mortality of approxi…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Which exercise boosts balance and jumping more for couch potatoes?
Knowledge-focused CompletedThe aim of this study was to compare the effects of Open Kinetic Chain (OKC) and Closed Kinetic Chain (CKC) exercises on dynamic balance, static balance, and vertical jump performance in sedentary individuals. A total of 68 sedentary individuals voluntarily participated in this …
Phase: NA • Sponsor: Lokman Hekim University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Early safety check for new c. diff drug in japanese volunteers
Knowledge-focused CompletedThe purpose of this study is to measure safety, tolerability and PK of a single dose of AZD5148 administered via IV bolus or IM injection in healthy Japanese participants.
Phase: PHASE1 • Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Moderna begins first human safety tests of new mRNA drug
Knowledge-focused OngoingThe purpose of this study is to test the safety of mRNA-0184 in healthy participants.
Phase: PHASE1 • Sponsor: ModernaTX, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New drug ABBV-722 tested in humans for first time
Knowledge-focused OngoingThis is a Phase 1, first-in-human study to investigate safety, tolerability, and pharmacokinetics of ABBV-722 after oral dosing in healthy adult participants.
Phase: PHASE1 • Sponsor: AbbVie • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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New bandage battle: do prototype foam dressings stick as well as the old ones?
Knowledge-focused CompletedThe purpose of this study is to evaluate two new prototype non-medicated multilayer foam dressings on healthy, intact skin. The study will find out how well two new prototype dressings stay in place as well as other dressing performance and safety factors when compared to corres…
Phase: NA • Sponsor: Smith & Nephew, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Digital dental scans put to the test against old-school molds
Knowledge-focused CompletedFor several decades now, modern procedures have allowed dentists to capture your teeth using digital cameras. This digital procedure is increasingly replacing traditional impressions with a viscous mass that hardens in the mouth. In the following study, the investigators want to…
Phase: NA • Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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Healthy volunteers needed to test drug interaction
Knowledge-focused OngoingThis is a single-center, open-label, two-period, fixed-sequence clinical study to evaluate the effect of Rifampicin on the pharmacokinetics of HSK31858 in healthy subjects
Phase: PHASE1 • Sponsor: Haisco Pharmaceutical Group Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Pain block study for back surgery withdrawn before it began
Symptom relief TerminatedSingle-center, randomized study will enroll 50 subjects who are scheduled for 1-3 level posterior laminectomy \& fusion. Study participants who are eligible for the posterior lumbar laminectomy and fusion procedure will be scheduled and also consented as a part of the study. Part…
Phase: NA • Sponsor: Corewell Health East • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC