Brain scans reveal how TMS may help depression
NCT ID NCT04278521
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how transcranial magnetic stimulation (TMS) changes brain connections in people with major depression. Researchers will use MRI scans to measure brain activity before and after TMS treatment. The study involves 54 adults aged 18-80 who are already receiving TMS as part of their care. The goal is to understand the brain mechanisms behind TMS, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Transcranial Magnetic Stimulation (TMS)
- What this could lead to
- If successful, this study could help explain how TMS works in the brain, potentially leading to better treatments for depression.
- What could go wrong
- This is a small observational study, not a treatment trial. It may not find clear results, and findings may not apply to all people with depression.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Massachusetts General Hospital
Boston, Massachusetts, 02129, United States
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