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116076 trials found · Page 5553 of 5804
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Virtual exercise coach tested for heart failure – but trial stops early
Symptom relief TerminatedThis study builds on the tested and refined HEART Camp intervention which has been shown to improve long-term adherence to exercise in individuals diagnosed with heart failure. HEART Camp Connect enhances HEART Camp by delivering the coaching via videoconference and providing acc…
Phase: NA • Sponsor: University of Nebraska • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Brain scans reveal why some people are more susceptible to placebos
Knowledge-focused ENROLLING_BY_INVITATIONExpectation effects on affective states are central to mechanisms relevant for mood disorders and their treatment. This study will test whether inter-individual differences in resting-state functional connectivity (rsFC) within emotion regulation networks is associated with affec…
Sponsor: Stefanie Brassen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Fasting for immunity: tiny study tests 36-Hour Water-Only fast
Knowledge-focused Recruiting nowThis is a clinical trial assessing the effects of fasting on the immune system in healthy adults. Immune profiling, gene expression profiling, and flow cytometry on peripheral blood mononuclear cells (PBMCs) will be performed and we hypothesize that a period of fasting will alter…
Phase: NA • Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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New pulse oximeter put to the test in extreme Low-Oxygen conditions
Knowledge-focused OngoingThe aim of this study is to determine the accuracy of devices called pulse oximeters, which measure blood oxygen by shining light through fingers, ears or other skin, without requiring blood sampling. Study will be used with patients at rest
Sponsor: Nihon Kohden • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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No-Needle patch could help spinal injury patients poop
Disease control CompletedPersons with spinal cord injury (SCI) have neurogenic bowel disorders which is associated with significant morbidity. The negative impact of bowel complications is often at the top of the list of problems reported by persons with SCI. Despite the magnitude of the problem of bowel…
Phase: EARLY_PHASE1 • Sponsor: James J. Peters Veterans Affairs Medical Center • Aim: Disease control
Last updated Jun 26, 2026 18:24 UTC
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Breaking language barriers in childhood cancer care
Knowledge-focused Recruiting nowThis study will seek to improve communication with Spanish speaking families and patients with Cancer and Blood Disorders.
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Denture Wearers' taste buds put to the test in new study
Knowledge-focused Recruiting nowTooth loss impacts taste abilities and food intake. Present study aims at pertaining the impact of teeth loss and the replacement by means of complete denture on taste and trigeminal abilities, and on food preferences, and taste appetence.
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Healthcare workers speak out: new survey exposes hidden violence on the job
Knowledge-focused CompletedWorkplace violence includes physical and verbal aggression as well as threatening behavior. All types of workplace violence incidents in health care are often under-reported, especially if there is no lasting physical injury.
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Gut microbiome study in kids with autoimmune diseases ends early
Knowledge-focused TerminatedTwo types of inflammatory and autoimmune diseases (excluding monogenic diseases) can be distinguished in children: those similar to adult diseases but with an early onset (type 1 diabetes, inflammatory diseases of the gastrointestinal tract, rheumatoid arthritis with anti-CCP ant…
Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Scientists probe gut to see how drugs really dissolve
Knowledge-focused CompletedIn vivo drug dissolution in the gastrointestinal (GI) tract is largely unmeasured. The purpose of this clinical study is to evaluate the in vivo drug dissolution and systemic absorption of modified release formulations of the BCS Class II drug Glipizide by direct sampling of stom…
Phase: PHASE1 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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Why did women skip a breast cancer trial? COVID money woes may be key
Knowledge-focused TerminatedThe purpose of this study is to find out whether factors that lead Women of Color to decline participation in the breast cancer screening trial EA1151 (TMIST) differ from non-women of color.
Sponsor: Eastern Cooperative Oncology Group • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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Smart braces chip tracks wear time in kids
Knowledge-focused CompletedThis randomized controlled trial aims to evaluate whether thermosensory wear-time documentation improves patient compliance of removable orthodontic appliances treated in a public health care clinic. The patients are children and adolescents.
Phase: NA • Sponsor: University of Helsinki • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Diabetes may change how fast the stomach empties before surgery
Knowledge-focused CompletedComparison of residual gastric volume measure by ultrasounds between diabetic and non-diabetic patients scheduled for elective surgery
Sponsor: Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Study checks safety of combining two pain drugs in abdominal surgery
Knowledge-focused CompletedThoracic epidural analgesia (TEA) is the gold standard analgesia of the laparotomy in major abdominal surgery and can be associated with intravenous lidocaine or subtituted by intravenous lidocaine when TEA is contraindicated and in order to reduce the use of the morphinics in th…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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New Frown-Line treatment shows promise in large trial
Symptom relief CompletedFacial lines that develop from repeated facial expression, such as glabellar lines (GL), are typically treated by selectively weakening specific muscles with small quantities of botulinum toxin. AGN-151586 is an investigational product being developed for the treatment of GL. The…
Phase: PHASE3 • Sponsor: AbbVie • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Heart device data drive: 1,000 patients help shape Tomorrow's implants
Knowledge-focused OngoingThe study is designed to collect data on Cardiovascular Implantable Electronic Device (CIED) information, implant procedure details, and/or patient characteristics to support development of future CIED products and procedures.
Sponsor: Medtronic Cardiac Rhythm and Heart Failure • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Electric toothbrush battle: which brush wins for whiter teeth?
Symptom relief CompletedThe objective of the present study was to compare the effects of reduction of extrinsic stains between 2 commercially available Oclean sonic toothbrushes in comparison with an Oral-B manual toothbrush.
Phase: NA • Sponsor: Sun Yat-sen University • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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New registry aims to track brain infection outcomes
Knowledge-focused Recruiting nowCentral Nervous System (CNS) infections are considered rare conditions but at the same time, they are emergencies whose diagnosis and treatment are time-dependent. They include several clinical syndromes, including meningitis, encephalitis, brain abscesses, and post-surgical meni…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Can a monitor read pain in sleeping kids?
Knowledge-focused CompletedThe Nociception Level (NoL) is an index obtained via a non-invasive monitor, that is currently used to assess nociception in anesthetized adults. The NoL index varies from 0 to 100. It increases in response to nociceptive stimuli. The objective of this study was to investigate if…
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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PTSD drug safety study halted early: what we know
Knowledge-focused TerminatedAbout 6.4% of the U.S. population suffers from posttraumatic stress disorder (PTSD). Trauma-focused psychotherapies are generally effective in PTSD, but responses vary greatly across individuals and PTSD subpopulations. Neurobiological factors impacted by life experiences, stress…
Phase: PHASE2 • Sponsor: Boston University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC