Could a blood pressure drug curb impulsive behaviors in Parkinson's?
NCT ID NCT03552068
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This pilot study tested whether clonidine, a drug used for high blood pressure, can reduce impulse control disorders (like gambling or overeating) in people with Parkinson's disease. 38 participants received either clonidine or a placebo for 8 weeks. The study measured changes in impulsive behavior using a special questionnaire. It's an early, small trial to see if this approach is worth further study.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Clonidine
What this could lead to
If it works, this could point toward a new treatment for impulse control problems in Parkinson's disease.
What could go wrong
This is a very small pilot study (38 people) and only a proof of concept. Clonidine is a blood pressure drug, so it may cause side effects like low blood pressure or drowsiness, and it may not help at all.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospices Civils de Lyon
Bron, France