Gut bacteria drug shows promise against blood disorder

NCT ID NCT03820817

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tested whether the oral antibiotic rifaximin can reduce abnormal proteins in people with monoclonal gammopathy, a condition that can lead to blood cancers. Fifty adults with different types of gammopathy took the drug to see if it lowered their immunoglobulin levels by at least 25%. The goal was to find a new way to control the disease by targeting bacteria in the gut.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Emory University Hospital/Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

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