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127005 trials found · Page 5346 of 6351
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Remote work may be reshaping our spines and screen habits
Knowledge-focused CompletedLow back pain and neck pain are common problems that affect people at certain times in their lives. These people constitute a significant part of the disease burden due to their recurrent complaints. People with low back and neck pain often seek medical attention. This situation …
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
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Texts and gadgets aim to keep kidney stones away
Prevention CompletedThe purpose of this study is to examine the feasibility of using sipIT tools (i.e., wrist-worn sensors, smart water bottles, mobile applications) to increase compliance with physician-recommended fluid consumption guidelines in participants with a history of urolithiasis.
Sponsor: University of Michigan • Aim: Prevention
Last updated Jun 26, 2026 18:19 UTC
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NIH launches biobank to unlock DNA secrets of Women's cancers
Knowledge-focused By invitation onlyBackground: A person s blood, tissue, and other samples contain DNA. Cancer is a disease of cells that are not working properly. It is caused by changes in DNA that build up. Researchers want to do future studies on DNA changes This may help them learn how to guide treatment for…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Sep 10, 2026 00:00 UTC
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New pain test may take guesswork out of pancreatitis treatment
Knowledge-focused Recruiting nowAbdominal pain in chronic pancreatitis (CP) affects up to 90% of patients during the course of their disease, and response to currently available therapies is suboptimal and unpredictable. The proposed clinical trial will evaluate the predictive capability of Pancreatic Quantitat…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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New sleep therapy aims to help veterans with memory loss get better rest
Symptom relief CompletedCognitive Behavioral Therapy for Insomnia (CBT-I) is the first-line treatment for chronic insomnia. However, cognitive impairments may limit progress in CBT-I for older Veterans with Mild Cognitive Impairment (MCI). This study will develop and pilot test Sleep-SMART (Sleep Sympto…
Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Eye surgery showdown: which oil removal method is safer?
Disease control Recruiting nowThe aim of our study is to compare between two techniques used for active SOR. The outcomes include efficiency and safety. Patients with silicon filled eyes and prepared for SOR 540 eyes of 505 patients (one eye in 470 patients, and both eyes in 35 patients) were enrolled in the…
Sponsor: Sohag University • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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PET scans shed light on mysterious fevers in hospital patients
Knowledge-focused CompletedRetrospective cohort study of inpatients at a South Australian tertiary hospital who underwent 18F FDG-PET/CT for investigation of undifferentiated fever or inflammatory syndrome. The aim is to investigate the utility of FDG-PET/CT in the investigation of suspected infection in h…
Sponsor: University of Adelaide • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Study finds community care may be better for teens with severe mental health issues
Knowledge-focused CompletedThis is a quasi-experimental longitudinal study to compare the outcomes of youth in a Psychiatric Residential Treatment Facility (PRTF) compared to youth in the community-based Child-Focused Assertive Community Treatment Team \[Child ACTT\] program. The hypothesis is that Child A…
Sponsor: Outcome Referrals, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Scientists launch major study to unravel hidrosadenitis mysteries
Knowledge-focused Recruiting nowOur primary objective with this cohort will be to define the different phenotypes of acute hidrosadenitis, the characterization of which is essential to define suitable therapeutic approaches. Indeed, our recent data allow us to note that there would be different phenotypes of ac…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:53 UTC
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Jaw injection may take the ouch out of wisdom tooth surgery
Symptom relief Stopped earlyPain, swelling, and trismus are common sequalae of surgical removal of impacted third molars. The aim of this study is to evaluate effect of local administration of betamethasone, into the pterygomandibular space, on these sequalae
Phase 3 • Sponsor: Shehab Ahmed Hamad • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Can more drops beat dry eye? new study tests three schedules
Symptom relief CompletedPhase II, comparative, controlled, multicenter, parallel group, open, randomized clinical study. The main outcome variable will be the Ocular Surface Disease Index (OSDI) questionnaire. Three dosage schemes of topical ophthalmic application of Multidose Lagricel® Ofteno (Sodium H…
Phase 2 • Sponsor: Laboratorios Sophia S.A de C.V. • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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New school program aims to catch teen mental health issues early
Knowledge-focused CompletedThe proposed research project provides a novel approach to screening, early assessment, and preventive interventions for high-risk youth in racial/ethnic/linguistically (REL)-diverse communities. * The investigators assess a health promotion intervention as a way of reducing tre…
Sponsor: Cambridge Health Alliance • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Internet therapy for obesity shows promise in new study
Symptom relief OngoingThere is a strong link between obesity and reduced quality of life as well as serious sequelae of diseases. Step by step is a treatment model that has been developed at the Obesity Unit, Orebro County Region and includes six group meetings over 6-8 months. The aim is to increase …
Sponsor: Region Örebro County • Aim: Symptom relief
Last updated Jun 26, 2026 17:04 UTC
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Plasma donation study: frequent Donors' health under the microscope
Knowledge-focused CompletedThis project is a randomized controlled non-inferiority study that aims to cover knowledge gaps about the composition and development of plasma proteins, inflammation markers and mental health in Norwegian, voluntary, and unpaid blood donors who donate plasma and blood. We will i…
Sponsor: Sykehuset Innlandet HF • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Study reveals why some women dismiss mammogram facts
Knowledge-focused CompletedIdentify the prevalence and predictors of reactance, self-exemption, disbelief, source derogation in reaction to evidence about mammography benefits and harms, and consequences for decision-making and trust.
Phase 2 • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Can education and support ease the burden of pulmonary hypertension?
Symptom relief CompletedThis study was conducted to evaluate the effect of the Dynamic Blended Learning Module developed for patients diagnosed with pulmonary hypertension (PH) on symptom management. Pulmonary hypertension is a chronic disease that can cause symptoms that make daily life difficult, suc…
Sponsor: Acibadem University • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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New injection could slash morphine use after spinal fusion
Symptom relief Recruiting nowThe aim of this study is to observe or not a reduction in the consumption of morphine within 72 hours of the realization of an erector spinae plane block when preparing for a lumbar spinal fusion.
Sponsor: Clinique Saint Jean, France • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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New nerve block could slash morphine use after back surgery
Symptom relief CompletedThe aim of this study is to observe or not a reduction in the consumption of morphine within 72 hours of the realization of an erector spinae plane block when preparing for a non-instrumented spine surgery.
Sponsor: Clinique Saint Jean, France • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Simple exercises may fix 'Tech Neck' and shoulder pain
Symptom relief OngoingRecently, many office workers and young people have postural abnormalities, including forward head posture (FHP) and rounded shoulder posture (RSP). Most of these patients often complain of pain in the entire scapular area, including the trapezius muscle. Few studies examined the…
Sponsor: Hallym University Dongtan Sacred Heart Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Gum graft showdown: own tissue vs. collagen matrix for better dental implants
Disease control CompletedThis investigator-initiated randomized controlled clinical trial evaluated changes in peri-implant soft tissue thickness in the aesthetic zone following soft tissue augmentation. Adult patients requiring single-tooth implant therapy in the aesthetic zone were randomly assigned to…
Sponsor: Medical Innovation Center Wroclaw • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC