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127005 trials found · Page 5340 of 6351
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Can acupuncture help COPD patients breathe easier?
Symptom relief Stopped earlyThe investigator is investigating if acupuncture may improve pulmonary function, exercise tolerance, stress and modulate the inflammatory effects of chronic obstructive pulmonary disease (COPD). The investigator would like to measure the effect of the combination of acupuncture w…
Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Walking analysis sheds light on rare genetic disorders
Knowledge-focused CompletedThe aim of this pilot study is to explore whether the knowledge and experience gained during the T-GaiD project (Treatment of Gait Disorders in Dravet Syndrome - NCT03857451) can be transferred to other populations with similar problems, i.e. motor and gait problems as a result o…
Sponsor: Universiteit Antwerpen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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New knife may speed up colon polyp removal
Symptom relief OngoingThis is a prospective, randomized trial that aims to study the efficacy and clinical outcomes of a novel Bipolar Knife vs. Monopolar Knives on patients who undergo endoscopic submucosal dissection (ESD) procedure at Baylor St. Luke's Medical Center.
Sponsor: Baylor College of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Scientists zap brains to unlock secrets of memory
Knowledge-focused CompletedThe participants will perform a cognitive control task. During the task, rhythmic trains of transcranial magnetic stimulation will be delivered to the prefrontal cortex and parietal cortex. Participants will be screened for their ability to perform the task. Magnetic resonance im…
Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Pumping iron for mental health: study tests if exercise boosts blood vessels in PTSD and anxiety
Knowledge-focused Recruiting nowThe purpose of this research study is to examine the effect of various forms of exercise training on blood vessel function in healthy individuals as well as individuals with mental health disorders (posttraumatic stress disorder (PTSD) and/or generalized anxiety disorder (GAD)).
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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App-Based study aims to predict COPD attacks before they happen
Knowledge-focused CompletedThe main objective of this RE-SAMPLE cohort study is to identify from a real-world data (RWD) set that will be collected, a subset of data that can be potentially used as important predictors and parameters for disease progression of COPD and complex chronic conditions, and multi…
Sponsor: Medisch Spectrum Twente • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Shockwave therapy may boost recovery from achilles pain, small study suggests
Symptom relief CompletedThis work is designed as a randomized clinical trial, in which the effects of a protocol of 12-week resistance training loading the Achilles tendon and low-energy focused extracorporeal shock wave therapy (ESWT) in patients with Achilles tendinopathy (AT) will be monitored. It is…
Sponsor: University Hospital, Motol • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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New lymphoma drug trial halted early after testing in 18 patients
Disease control Stopped earlyThe purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK), immunogenicity and preliminary efficacy of VAY736 alone or in combination with other therapies in patients with NHL in a platform trial.
Phase 1 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Which injection works best for thumb tendon pain?
Symptom relief Recruiting nowThe aim of the study is to determine whether or not extra-sheath steroid injections are inferior to intra-sheath steroid injections in the treatment of DeQuervain's Tenosynovitis. Patients will be randomized to either the intra-sheath group or the extra-sheath group and their pr…
Phase 4 • Sponsor: University of California, Davis • Aim: Symptom relief
Last updated Jul 08, 2026 00:00 UTC
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Heart study explores Yoga's effect on genes
Knowledge-focused Stopped earlyThe aim of the prospective randomized single center study is to evaluate the effect of a short-term (16 weeks) yoga program on micro RNA (miRNA) expression and cardiovascular disease (CVD) risk factors in patients with CVD.
Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Can genes predict aggressive MS? new study aims to find out
Knowledge-focused Recruiting nowMS is a heterogeneous disease either in its response to treatment or clinical manifestation. Indeed, the natural history of MS is varying from a benign condition to a devastating and rapidly incapacitating disease. Clinical heterogeneity could also be cellular and / or molecular.…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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New bladder cancer drug tested before surgery
Disease control Ongoinghe primary objective is to characterize the safety profile of UGN-201 in patients with urothelial carcinoma undergoing radical cystectomy. Corresponding primary endpoint: Toxicity of concern (TOX) will be monitored until 30 days after surgery or until the patient meets the surge…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Aug 08, 2026 00:03 UTC
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Can a restless legs drug ease opioid withdrawal?
Symptom relief Stopped earlyThe investigators propose to test the use of pramipexole in patients being treated for Opioid Use Disorder to test its ability to reduce symptoms of both Restless Legs Syndrome and protracted opioid withdrawal and thereby promote initiation, engagement, and retention in treatment…
Phase 2/3 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Ambulance crews train to cut medication mistakes
Knowledge-focused CompletedMedication administration events have the potential to cause patient harm. Frequency of medication administration events in the ambulance services is less known. Effective teamwork has been described as paramount for providing safe and effective patient care in the high-risk ambu…
Sponsor: Sykehuset Innlandet HF • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Potassium pills may shield your arteries from salt damage
Knowledge-focused OngoingThis study will test whether potassium supplementation can reduce the deleterious effect of a high sodium diet on blood vessel function, blood pressure reactivity and autonomic nervous system function in apparently healthy adults.
Sponsor: University of Delaware • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Can fixing reflux fix your esophagus? new study investigates
Knowledge-focused Recruiting nowThis is a combined retro- and prospective, monocentric study. All patients who underwent or are planned for laparoscopic partial fundoplication (180° anterior or 270° posterior) between 2020-2023 are assessed for preoperative ineffective esophageal motility (IEM). The main hypot…
Sponsor: Prof Urs Zingg • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Walnut wonder: daily snack may reshape gut bacteria and fight colon cancer
Knowledge-focused CompletedThe purpose of this research study is to examine whether adding walnuts to your diet can have a beneficial effect on the gut bacteria population, inflammatory markers in the blood, and the tissue that lines the inside of the colon.
Sponsor: UConn Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Free lyft rides may speed up liver transplant waitlisting
Knowledge-focused CompletedWe propose a rideshare-supported intervention that leverages a partnership with Lyft Health, a HIPAA-secured logistics solution that enables us to provide reliable and efficient transportation for patients. Lyft rides will be provided to patients for any transplant-related medica…
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Gene study may explain why some breast cancers resist hormone therapy
Knowledge-focused Stopped earlyThis stage IV trial examines how a mutation in HSD3B1 (1245C) gene affects treatment of stage I-III breast cancer. This trial may help researchers determine if mutations in HSD3B1 decreases the efficacy of aromatase inhibitor therapy such as letrozole. Letrozole may stop the grow…
Phase 4 • Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Tiny muscle biopsies could unlock secrets of cancer wasting
Knowledge-focused Recruiting nowUntil now, cancer is still associated with high morbidity and mortality, and is therefore a big issue for the public health. Colorectal cancer is the second leading cause of cancer death in developed countries. In advanced colorectal cancer, 60% of these patients develop cachexia…
Sponsor: Hasselt University • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:09 UTC