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Which injection works best for thumb tendon pain?

NCT ID NCT04895956

Symptom relief Sponsor: University of California, Davis Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study tests whether injecting steroids just outside the tendon sheath works as well as injecting inside the sheath for De Quervain's tenosynovitis, a painful thumb condition. 80 adults with moderate to severe pain will receive one of the two injections and report their pain levels after 6 weeks and 6 months. The goal is to find a simpler, equally effective treatment option.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2022

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Signed informed consent from the patient exclusively and not a legal representative * Clinically diagnosed with De Quervain's * VAS score of at least 40mm pre-injection * Life expectancy greater than 1 year Exclusion Criteria: * Having previously undergone steroid injection in the treatment of De Quervain's * Having previously undergone surgery for De Quervain's in the affected wrist * Having previously undergone steroid injection and failed in the treatment of trigger finger * Allergies to lidocaine or dexamethasone * Underlying serious medical conditions that would place the patient at risk * Past history of hypothyroidism or rheumatoid arthritis * Pregnant women * Prisoners

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Conditions

The condition(s) this trial relates to.

de Quervain disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

De Quervain tenosynovitis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • UC Davis Health, Department of Orthopaedics

    RECRUITING

    Sacramento, California, 95817, United States