De Quervain disease
MONDO:0006721Stenosing tenosynovitis of the abductor pollicis longus and extensor pollicis brevis tendons in the first dorsal wrist compartment. The presenting symptoms are usually pain and tenderness at the radial styloid. The cause is almost always related to overuse injury or is associated with rheumatoid arthritis.
Also known as: radial styloid tenosynovitis
26 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
Vitamin E-Infused hip implants face off against ceramic in wear test
Disease control Recruiting nowThis study compares two types of hip replacement materials in 100 adults aged 18 to 65 who need a total hip replacement. One group gets a ceramic-on-polyethylene implant where the polyethylene is infused with vitamin E to reduce wear. The other group gets a standard ceramic-on-ce…
Phase: NA • Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
-
Can light therapy unlock stiff fingers?
Symptom relief Recruiting nowThis trial tests whether adding low-level laser therapy to a standard splint can ease the pain and locking of trigger finger, a common hand condition. About 91 people with trigger finger will receive either real laser treatment or a sham (inactive) laser, three times a week for f…
Phase: NA • Sponsor: Dokuz Eylul University • Aim: Symptom relief
Last updated Aug 09, 2026 00:00 UTC
-
Shock wave or splint? new study tests best treatment for trigger finger
Symptom relief Recruiting nowThis study compares two common treatments for trigger finger: shock wave therapy and a finger splint. Researchers will enroll 54 adults with early-stage trigger finger to see which approach better reduces pain and improves hand function. The goal is to find out if shock wave ther…
Phase: NA • Sponsor: Hacettepe University • Aim: Symptom relief
Last updated Aug 07, 2026 00:00 UTC
-
Which injection works best for thumb tendon pain?
Symptom relief Recruiting nowThis study tests whether injecting steroids just outside the tendon sheath works as well as injecting inside the sheath for De Quervain's tenosynovitis, a painful thumb condition. 80 adults with moderate to severe pain will receive one of the two injections and report their pain …
Phase: PHASE4 • Sponsor: University of California, Davis • Aim: Symptom relief
Last updated Jul 08, 2026 00:00 UTC
-
New study tests best rehab after steroid shot for thumb tendon pain
Symptom relief Recruiting nowThis study looks at 134 people with De Quervain's disease, a painful thumb tendon condition. All participants get a steroid injection, then either standard physiotherapy or a program of eccentric exercises. The goal is to see which approach better reduces pain and improves hand f…
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
-
Which incision is best for trigger finger? new study aims to find out
Symptom relief Recruiting nowThis study compares two different skin cuts used during trigger finger surgery to see which one helps patients recover better. About 200 adults with trigger finger will be randomly assigned to get either a straight cut along the finger or a cut across the palm crease. Researchers…
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
-
New study aims to ease pain after hip replacement
Symptom relief Recruiting nowThis study tests two ways to manage pain after hip replacement surgery. One group gets a nerve block plus a second nerve block; the other gets a nerve block plus wound numbing. The goal is to see which method reduces pain and the need for opioid painkillers. About 102 adults havi…
Phase: NA • Sponsor: Ospedale Edoardo Bassini • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
-
Splint or exercise? new study aims to settle best treatment for thumb tendonitis
Symptom relief Recruiting nowThis study compares two common conservative treatments for De Quervain's tenosynovitis, a painful thumb tendon condition: a static hand-wrist splint versus home-based exercise therapy. Forty adults with acute or subacute pain will be tracked for changes in pain, wrist function, a…
Phase: NA • Sponsor: Konya Beyhekim Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
-
Hip replacement patients monitored for years to improve future surgeries
Knowledge-focused Recruiting nowThis study will follow 200 people who have had a complex or revision hip replacement at University Hospitals Leuven. The goal is to track how many need another surgery and why, and to improve care by learning from real-world results. No new treatment is being tested—this is an ob…
Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
-
Which knee implant gets you back in the game? new study aims to find out.
Knowledge-focused Recruiting nowThis study looks at how often people can return to sports at least three years after total knee replacement. It compares three different types of knee prostheses to see if one type leads to better sports participation. The study will include 660 adults who had their first knee re…
Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC