New exercise approach tested for thumb tendon pain

NCT ID NCT06296472

First seen May 07, 2026 · Last updated Jun 19, 2026 · Updated 11 times

Summary

This study tests whether a specific eccentric exercise program works better than standard physiotherapy for people with De Quervain's disease, a painful thumb tendon condition. All 134 participants first receive a steroid injection guided by ultrasound. Then one group does eccentric exercises and wears a brace for 4 weeks, while the other group does generic exercises and wears the same brace. The main goal is to see which group has less pain and better hand function.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Istituto Ortopedico Rizzoli

    RECRUITING

    Bologna, 40136, Italy

    Contact Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

corticosteroid injection and physiotherapy (eccentric or standard exercises)

What this could lead to

If successful, this could point toward a more effective exercise program to reduce pain and improve hand function after a steroid injection for De Quervain's disease.

What could go wrong

This is a small, early-stage trial (134 people) comparing two exercise approaches, so it may not show a clear difference. Results may not apply to everyone with the condition.

Conditions

The condition(s) this trial relates to.

de Quervain disease tenosynovitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.