De Quervain disease
MONDO:0006721Stenosing tenosynovitis of the abductor pollicis longus and extensor pollicis brevis tendons in the first dorsal wrist compartment. The presenting symptoms are usually pain and tenderness at the radial styloid. The cause is almost always related to overuse injury or is associated with rheumatoid arthritis.
Also known as: radial styloid tenosynovitis
26 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Antioxidant pill may cut opioid use after surgery
Symptom relief Not yet recruitingThis study tests whether taking N-acetylcysteine (NAC), a common supplement, before and after hand or foot surgery can reduce pain and the need for opioid painkillers. About 80 adults will be randomly assigned to take NAC or a placebo for 14 days. Researchers will track pain, fun…
Phase: PHASE2 • Sponsor: University of Arizona • Aim: Symptom relief
Last updated Jul 19, 2026 00:00 UTC
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Could a simple pill boost knee replacement recovery?
Symptom relief Not yet recruitingThis study tests whether taking tranexamic acid pills for a week after knee replacement surgery helps people recover better. 350 adults having their first knee replacement will receive either the drug or a placebo. Researchers will track pain, stiffness, and function for up to 2 …
Phase: NA • Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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New study eyes Tirzepatide's hidden impact on joints and heart
Knowledge-focused Not yet recruitingThis observational study in Mexico will follow 30 adults already taking tirzepatide for conditions like diabetes or obesity. Researchers will use MRI scans of the knees, CT scans of the heart, and body composition tests to see how the drug affects cartilage, heart fat, and overal…
Sponsor: JULIO GRANADOS MONTIEL • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Hand rehab revolution? early data may predict recovery months ahead
Knowledge-focused Not yet recruitingThis study follows 60 adults with hand or upper limb injuries to see if improvements in the first weeks of rehab can predict function months later. A digital tool created by a therapist tracks progress and patient feedback. The goal is to help clinicians make better, data-driven …
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Study explores how conversations shape patient choices on x-rays and MRIs
Knowledge-focused Not yet recruitingThis study looks at how having a structured, values-based conversation affects people's decisions about diagnostic imaging tests for common musculoskeletal conditions like arthritis, carpal tunnel syndrome, and tendon problems. About 220 adults from a specialty clinic will read a…
Phase: NA • Sponsor: University of Texas at Austin • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:22 UTC