Can genes predict aggressive MS? new study aims to find out

NCT ID NCT04873492

Recruiting now Knowledge-focused Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is collecting blood, saliva, and stool samples from 130 people with multiple sclerosis (MS) and healthy volunteers. Researchers will analyze the genetic activity of immune cells to understand why some patients have a mild form of MS while others become severely disabled within a few years. The goal is to identify early markers that could predict a poor outcome, but this is an observational study and does not test any treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors predict early which MS patients will have a severe course, enabling more personalized treatment decisions.
What could go wrong: This is an observational study, not a treatment trial. It may not find clear markers, and any findings would need years of further research to become useful in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE SCLEROSIS

Contacts and locations

Locations

Nantes University Hospital
RECRUITING

Nantes, Loire-Atlantique, 44093, France

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