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116076 trials found · Page 5016 of 5804
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Promising combo for eye cancer stalls after only 3 patients enrolled
Disease control TerminatedThis phase II trial studies how well stereotactic body radiation therapy and aflibercept work in treating patients with uveal melanoma. Stereotactic body radiation therapy is a specialized radiation therapy that sends x-rays directly to the tumor using smaller doses over several …
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Which painkiller works best after a nose job? new study has answers.
Symptom relief CompletedThe primary purpose of the study is to determine adequacy of postoperative pain control after nasal surgery in patients prescribed Acetaminophen (325mg) + Hydrocodone (5mg) compared to Acetaminophen(325mg) + Ibuprofen (200mg)for a period of 5 days after nasal surgery. To assess t…
Phase: PHASE2 • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Leg artery study halted: did platelet screening help?
Disease control TerminatedThis is a randomized controlled trial designed to evaluate the role of screening for and intervening on patients with high on treatment platelet reactivity undergoing lower extremity arterial endovascular interventions.
Phase: PHASE3 • Sponsor: Marissa Jarosinski • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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Wrinkle-Zapping device may double as dry eye remedy
Symptom relief CompletedPilot study where effect of standard Tixel treatment as used for periorbital wrinkles would be assessed on Dry Eye Disease symptoms and signs
Phase: NA • Sponsor: Aston University • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Shock therapy for needle pain: TENS device tested on psoriasis patients
Symptom relief OngoingThe purpose of this research study is to determine the efficacy of TENS therapy in reducing the pain experienced by patients during and after the injection of biological medications. The study team is interested in recording the level of pain reduction from TENS therapy to determ…
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Bone screw safety under review: new study follows 51 patients
Disease control OngoingThe objective of this retrospective enrollment/prospective follow up study is to collect data confirming safety, performance, and clinical benefits of the Biomet Cannulated Bone Screw System (Implants and Instrumentation) when used according to the approved Indications for Use (I…
Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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Dye test aims to improve ovarian cancer staging
Knowledge-focused CompletedThe purpose of this study is to find out how well ovarian sentinel lymph nodes (SLNs) can be identified with indocyanine green (ICG) dye during risk-reducing ovarian surgery.
Phase: EARLY_PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Could vitamin B12 help fight septic shock?
Disease control CompletedThis study will randomize 20 septic shock patients to receive either a single 5 gram dose of IV vitamin B12 (Cyanokit® Meridian Medical Technologies, Columbia, MD) versus placebo in addition to standard of care to test the feasibility of completing clinical and laboratory protoco…
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Brain scans reveal how imagining acupuncture may ease knee pain
Knowledge-focused CompletedThe aim of this study is to investigate brain response and connectivity changes evoked by video-guided acupuncture imagery treatment (VGAIT) and verum and sham acupuncture in knee osteoarthritis patients to elucidate the underlying brain mechanisms of mind-body interaction, image…
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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New CT method may help doctors predict lung disease severity
Knowledge-focused CompletedPathophysiological mechanisms leading to pulmonary hypertension (PH) are complex. Quantitative computed tomography (QCT) can help us to study morphological alterations in patients with PH. These CT morphometrics are useful to predict the degree of PH severity at least in PH secon…
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Childhood neglect study tracks teen brains and behavior
Knowledge-focused CompletedThis study follows children into adolescence who were first randomized to intervention condition in infancy.
Phase: NA • Sponsor: University of Delaware • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Which advance care planning method works best for cancer patients?
Knowledge-focused CompletedThe overall goal of this study is to identify the most effective and efficient advance care planning (ACP) strategy for patients with advanced cancer. The specific aims are to: Aim 1. Compare the effectiveness of in-person, facilitated ACP versus web-based ACP on patient and fa…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New registry aims to solve blood thinner dilemma for heart patients needing surgery
Knowledge-focused CompletedThere are key differences today in clinical practice regarding perioperative management of post-PCI patients on DAPT undergoing NCS. Moreover, there are significant differences between bridging agents, and improved safety of current-generation DES. Given the significant limitatio…
Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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New CT model could forecast bladder cancer comeback
Knowledge-focused CompletedThis retrospective study included 316 bladder cancer patients
Sponsor: Lian Yang • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Virtual reality training aims to improve arm control in ataxia
Symptom relief Recruiting nowThe purpose of this study is to test for benefits of reinforcement based training paradigm versus standard practice over weeks for improving reaching movements in people with ataxia.
Phase: NA • Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc. • Aim: Symptom relief
Last updated Jul 03, 2026 00:00 UTC
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Laser zaps face veins in scleroderma patients – 21 test it out
Symptom relief CompletedThis single-center, prospective, open-label, quasi-experimental, intra-individual comparative study will include a consecutive cohort of 21 patients with diffuse or limited, minimally active scleroderma with 3 to 30 years of evolution. Patients will have 4 sessions of pulsed dye…
Phase: NA • Sponsor: University Hospital, Caen • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Can a school program curb violence disparities for students of color?
Knowledge-focused CompletedThe investigators propose to develop and evaluate Link for Equity, a trauma-informed system of care. Link, a system of support for ACE-affected children, is composed of universal school Trauma-Informed Care. Preventing Racism through Awareness and Action (PRAA) is a perspective-t…
Phase: NA • Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:56 UTC
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Vitamin c may cut anemia drug needs in kidney patients
Disease control CompletedThe study aimed to evaluate the safety and efficacy of oral vitamin C administration on erythropoietin dosing requirement in end-stage renal disease patients on regular hemodialysis.
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New MRI technique could shed light on stomach disorder
Knowledge-focused OngoingThe study is to lay the groundwork for non invasive imaging of the GI tract and the brain gut interaction
Phase: NA • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Can a tailored home workout help cancer survivors with chronic conditions feel better?
Symptom relief CompletedA home-based, tailored, technology-enhanced home-based exercise program (iHBE) using a combination of the integrated mobile technologies (wearable device and phone application) and tailored home-based exercise will be pilot tested. Participants will choose one of the four home-ba…
Phase: NA • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC