New hope for kidney stone sufferers: supplement may stop painful recurrences

NCT ID NCT06003348

First seen Jun 15, 2026 · Last updated Jun 23, 2026 · Updated 2 times

Summary

This study tests whether hydroxycitrate, a molecule similar to citrate, can reduce the recurrence of calcium phosphate kidney stones. Researchers will give 25 stone formers either hydroxycitrate, potassium citrate, or a placebo, and measure how well their urine prevents stone formation. The goal is to find a simple, accessible therapy to keep these painful stones from coming back.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390-8885, United States

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hydroxycitrate (dietary supplement)

What this could lead to

If it works, this could offer a new way to prevent calcium phosphate kidney stones from coming back.

What could go wrong

This is a small early-phase trial with only 25 people, so results may not apply to everyone. The supplement is not FDA approved or regulated.

Conditions

The condition(s) this trial relates to.

nephrolithiasis urolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.