New hope for kidney stone sufferers: supplement may stop painful recurrences

NCT ID NCT06003348

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether hydroxycitrate, a molecule similar to citrate, can reduce the recurrence of calcium phosphate kidney stones. Researchers will give 25 stone formers either hydroxycitrate, potassium citrate, or a placebo, and measure how well their urine prevents stone formation. The goal is to find a simple, accessible therapy to keep these painful stones from coming back.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Hydroxycitrate (dietary supplement)
What this could lead to
If it works, this could offer a new way to prevent calcium phosphate kidney stones from coming back.
What could go wrong
This is a small early-phase trial with only 25 people, so results may not apply to everyone. The supplement is not FDA approved or regulated.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390-8885, United States

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Other studies related to the condition(s) this trial covers.